Suzetrigine
Journavx (suzetrigine) is a small molecule pharmaceutical. Suzetrigine was first approved as Journavx on 2025-01-30.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
Journavx
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Suzetrigine
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| JOURNAVX | Vertex Pharmaceuticals | N-219209 RX | 2025-01-30 | 1 products, RLD, RS |
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| journavx | New Drug Application | 2026-10-02 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| acute pain | — | D059787 | R52 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
59 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pain | D010146 | EFO_0003843 | R52 | 14 | — | 4 | 4 | — | 22 |
| Postoperative pain | D010149 | — | G89.18 | — | 1 | 5 | 13 | 1 | 20 |
| Acute pain | D059787 | — | R52 | 1 | 3 | 3 | 5 | — | 12 |
| Agnosia | D000377 | EFO_0007136 | F88 | — | — | 2 | 3 | — | 5 |
| Pain management | D059408 | — | — | — | — | 2 | 2 | — | 4 |
| Knee osteoarthritis | D020370 | EFO_0004616 | M17 | — | — | — | 2 | — | 2 |
| Osteoarthritis | D010003 | EFO_0002506 | M15-M19 | — | — | — | 2 | — | 2 |
| Skin neoplasms | D012878 | EFO_0004198 | C44 | — | — | — | 2 | — | 2 |
| Mohs surgery | D015580 | — | — | — | — | — | 2 | — | 2 |
| Pelvic organ prolapse | D056887 | EFO_0004710 | — | — | — | — | 2 | — | 2 |
Show 8 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Diabetic neuropathies | D003929 | EFO_1000783 | — | — | 1 | 3 | — | — | 4 |
| Randomized controlled trials as topic | D016032 | — | — | — | — | 2 | — | — | 2 |
| Replacement arthroplasty hip | D019644 | — | — | — | — | 1 | — | — | 1 |
| Bariatric surgery | D050110 | — | — | — | — | 1 | — | — | 1 |
| Ureteroscopy | D018666 | — | — | — | — | 1 | — | — | 1 |
Indications Phases 2
No data
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Renal insufficiency | D051437 | — | N19 | 1 | — | — | — | — | 1 |
| Pain threshold | D017288 | — | — | 1 | — | — | — | — | 1 |
| Common cold | D003139 | EFO_0007214 | J00 | 1 | — | — | — | — | 1 |
| Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Replacement arthroplasty | D019643 | — | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Suzetrigine |
| INN | — |
| Description | Suzetrigine, sold under the brand name Journavx, is a medication used for the management of pain. It is a non-opioid, small-molecule analgesic that works as a selective inhibitor of Nav1.8-dependent pain-signaling pathways in the peripheral nervous system, avoiding the addictive potential of opioids. Suzetrigine is taken by mouth.
|
| Classification | Small molecule |
| Drug class | sodium channel blockers, signal transduction modulators |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | COc1c([C@@H]2[C@H](C)[C@](C)(C(F)(F)F)O[C@H]2C(=O)Nc2ccnc(C(N)=O)c2)ccc(F)c1F |
Identifiers
| PDB | — |
| CAS-ID | 2649467-58-1 |
| RxCUI | — |
| ChEMBL ID | CHEMBL5314487 |
| ChEBI ID | — |
| PubChem CID | 156445116 |
| DrugBank | DB18927 |
| UNII ID | — |
Target
No data
Variants
No data
Financial
No data
Trends
No data
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
1,107 adverse events reported
View more details
© 2020-2025 Collaborative Drug Discovery Inc. (CDD) | Terms of Use