Suxamethonium
Suxamethonium is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against acetylcholine receptor subunit alpha.
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Commercial
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| anectine | New Drug Application | 2023-11-29 |
| anectine civ | New Drug Application | 2024-03-13 |
| anectine nov | New Drug Application | 2024-03-13 |
| quelicin | New Drug Application | 2023-05-05 |
| succinylcholine | ANDA | 2024-02-25 |
| succinylcholine chloride | ANDA | 2024-10-16 |
Indications
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Agency Specific
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Patent Expiration
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Clinical
Clinical Trials
89 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Depressive disorder | D003866 | EFO_1002014 | F32.A | 1 | — | — | 4 | 5 | 10 |
| Depression | D003863 | — | F33.9 | — | — | — | 5 | 5 | 10 |
| Neuromuscular blockade | D019148 | — | — | — | 1 | 1 | 3 | 2 | 7 |
| Anesthesia | D000758 | — | — | — | — | — | 3 | 4 | 7 |
| Intratracheal intubation | D007442 | — | — | — | 1 | 1 | 2 | 2 | 6 |
| Disease | D004194 | EFO_0000408 | R69 | — | 1 | — | 2 | 2 | 5 |
| Intubation | D007440 | — | — | — | — | — | 1 | 4 | 5 |
| Major depressive disorder | D003865 | EFO_0003761 | F22 | — | — | — | 2 | 2 | 4 |
| Electroconvulsive therapy | D004565 | — | — | — | — | — | 1 | 3 | 4 |
| Cesarean section | D002585 | — | — | — | — | — | 2 | 1 | 3 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Myalgia | D063806 | HP_0003326 | M79.1 | — | 2 | 4 | — | 3 | 7 |
| Fasciculation | D005207 | — | R25.3 | — | — | 2 | — | 2 | 4 |
| Substance-related disorders | D019966 | EFO_0003890 | F13 | — | 1 | 1 | — | — | 1 |
| Colectomy | D003082 | — | — | — | 1 | 1 | — | — | 1 |
| Shock | D012769 | — | R57.1 | — | — | 1 | — | — | 1 |
| Wounds and injuries | D014947 | — | T14.8 | — | — | 1 | — | — | 1 |
| Coma | D003128 | HP_0001259 | R40.2 | — | — | 1 | — | — | 1 |
| Morbid obesity | D009767 | EFO_0001074 | — | — | 1 | 1 | — | — | 1 |
| Obesity | D009765 | EFO_0001073 | E66.9 | — | 1 | 1 | — | — | 1 |
| Postoperative pain | D010149 | — | G89.18 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 1 | 1 | — | — | 1 | 2 |
| Gastric bypass | D015390 | EFO_0005244 | — | — | 1 | — | — | — | 1 |
Indications Phases 1
No data
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Patient satisfaction | D017060 | — | — | — | — | — | — | 2 | 2 |
| Pain | D010146 | EFO_0003843 | R52 | — | — | — | — | 2 | 2 |
| Arthritis | D001168 | HP_0001369 | M05-M14 | — | — | — | — | 1 | 1 |
| Pharyngitis | D010612 | — | R07.0 | — | — | — | — | 1 | 1 |
| Pancreatic diseases | D010182 | — | K86.9 | — | — | — | — | 1 | 1 |
| Biliary tract diseases | D001660 | EFO_0009534 | K83.9 | — | — | — | — | 1 | 1 |
| Hypercapnia | D006935 | — | — | — | — | — | — | 1 | 1 |
| Adrenal insufficiency | D000309 | — | — | — | — | — | — | 1 | 1 |
| Obstetric labor complications | D007744 | — | — | — | — | — | — | 1 | 1 |
| Pregnancy rate | D018873 | — | — | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Suxamethonium |
| INN | suxamethonium chloride |
| Description | Succinylcholine is a quaternary ammonium ion that is the bis-choline ester of succinic acid. It has a role as a neuromuscular agent, a muscle relaxant and a drug allergen. It is a quaternary ammonium ion and a succinate ester. |
| Classification | Small molecule |
| Drug class | quaternary ammonium derivatives; quaternary ammonium derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C |
Identifiers
| PDB | — |
| CAS-ID | 306-40-1 |
| RxCUI | — |
| ChEMBL ID | CHEMBL703 |
| ChEBI ID | 45652 |
| PubChem CID | 5314 |
| DrugBank | DB00202 |
| UNII ID | J2R869A8YF (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
PubMed Central
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Additional graphs summarizing 8,925 documents
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Safety
Black-box Warning
Black-box warning for: Anectine, Anectine civ, Anectine nov, Quelicin, Succinylcholine, Succinylcholine chloride
Adverse Events
Top Adverse Reactions
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3,017 adverse events reported
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