Enjaymo(sutimlimab)
Enjaymo (sutimlimab) is an antibody pharmaceutical. Sutimlimab was first approved as Enjaymo on 2022-02-04. It has been approved in Europe to treat hemolysis and hemolytic anemia autoimmune. The pharmaceutical is active against complement C1s subcomponent.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Therapeutic Areas
Trade Name
FDA
EMA
Enjaymo
Drug Products
FDA
EMA
Reference product - 351(a)
Reference product - 351(a)
Interchangeable product - 351(k)
Interchangeable product - 351(k)
Biosimilar product - 351(k)
Biosimilar product - 351(k)
Sutimlimab
Tradename | Proper name | Company | Number | Date | Products |
|---|---|---|---|---|---|
| Enjaymo | sutimlimab-jome | Bioverativ | N-761164 RX | 2022-02-04 | 1 products |
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| enjaymo | Biologic Licensing Application | 2024-02-21 |
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
Expiration | Code | ||
|---|---|---|---|
sutimlimab, Enjaymo, Bioverativ Therapeutics, Inc. | |||
| 2029-02-04 | Orphan excl. | ||
Patent Expiration
No data
HCPCS
Code | Description |
|---|---|
| J1302 | Injection, sutimlimab-jome, 10 mg |
Clinical
Clinical Trials
6 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
No data
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hemolytic anemia autoimmune | D000744 | EFO_1001264 | D59.12 | 1 | — | 3 | — | 1 | 5 |
Indications Phases 2
No data
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Thrombocytopenic purpura idiopathic | D016553 | EFO_0007160 | D69.3 | 1 | — | — | — | — | 1 |
| Thrombocytopenia | D013921 | HP_0001873 | D69.6 | 1 | — | — | — | — | 1 |
| Thrombocytopenic purpura | D011696 | — | — | 1 | — | — | — | — | 1 |
| Purpura | D011693 | HP_0000979 | D69.2 | 1 | — | — | — | — | 1 |
| Chronic kidney failure | D007676 | EFO_0003884 | N18.9 | 1 | — | — | — | — | 1 |
| Bullous pemphigoid | D010391 | EFO_0007187 | L12 | 1 | — | — | — | — | 1 |
| Hemolytic anemia | D000743 | — | D55-D59 | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Sutimlimab |
| INN | sutimlimab |
| Description | Sutimlimab, sold under the brand name Enjaymo, is a monoclonal antibody that is used to treat adults with cold agglutinin disease (CAD). It is given by intravenous infusion. Sutimlimab prevents complement-enhanced activation of autoimmune human B cells in vitro.
|
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297832 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | GNWE7KJ995 (ChemIDplus, GSRS) |
Target
Agency Approved
C1S
C1S
Organism
Homo sapiens
Gene name
C1S
Gene synonyms
NCBI Gene ID
Protein name
complement C1s subcomponent
Protein synonyms
basic proline-rich peptide IB-1, C1 esterase, Complement component 1 subcomponent s, complement component 1, s subcomponent
Uniprot ID
Mouse ortholog
C1s2 (317677)
complement C1s-1 subcomponent (Q8CFG8)
Alternate
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 285 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
118 adverse events reported
View more details
© 2020-2024 Collaborative Drug Discovery Inc. (CDD) | Terms of Use