Sulfinpyrazone
Anturane (sulfinpyrazone) is a small molecule pharmaceutical. Sulfinpyrazone was first approved as Anturane on 1982-01-01. It is used to treat angina pectoris, coronary disease, gout, and myocardial infarction in the USA. The pharmaceutical is active against solute carrier family 22 member 12. In addition, it is known to target fMet-Leu-Phe receptor.
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Drug
General
| Drug common name | Sulfinpyrazone |
| INN | sulfinpyrazone |
| Description | Sulfinpyrazone is a sulfoxide and a member of pyrazolidines. It has a role as a uricosuric drug. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | O=C1C(CC[S+]([O-])c2ccccc2)C(=O)N(c2ccccc2)N1c1ccccc1 |
Identifiers
| PDB | — |
| CAS-ID | 57-96-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL832 |
| ChEBI ID | 9342 |
| PubChem CID | 5342 |
| DrugBank | DB01138 |
| UNII ID | V6OFU47K3W (ChemIDplus, GSRS) |
Target
Agency Approved
SLC22A12
SLC22A12
Organism
Homo sapiens
Gene name
SLC22A12
Gene synonyms
OATL4, URAT1
NCBI Gene ID
Protein name
solute carrier family 22 member 12
Protein synonyms
Organic anion transporter 4-like protein, Renal-specific transporter, RST, solute carrier family 22 (organic anion/cation transporter), member 12, solute carrier family 22 (organic anion/urate transporter), member 12, URAT1, Urate anion exchanger 1, urate anion transporter 1, urate transporter 1, Urate:anion antiporter SLC22A12
Uniprot ID
Mouse ortholog
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Safety
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10 adverse events reported
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