Brand Name | Status | Last Update |
---|---|---|
azulfidine | New Drug Application | 2025-04-08 |
sulfasalazine | NDA authorized generic | 2025-05-29 |
sulfasalazine delayed-release | 2007-08-31 | |
sulfazalazine | 2007-08-31 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Arthritis | D001168 | EFO_0005856 | M05-M14 | — | — | — | 3 | — | 3 |
Rheumatoid arthritis | D001172 | EFO_0000685 | M06.9 | — | — | — | 2 | — | 2 |
Juvenile arthritis | D001171 | EFO_1002007 | M08 | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Diabetic foot | D017719 | EFO_1001459 | — | — | 3 | — | — | — | 3 |
Necrosis | D009336 | — | — | — | 1 | — | — | 1 | 2 |
Glioblastoma | D005909 | EFO_0000515 | — | 2 | 1 | — | — | — | 2 |
Systemic lupus erythematosus | D008180 | EFO_0002690 | M32 | — | 1 | — | — | 1 | 2 |
Vasculitis | D014657 | EFO_0006803 | M31 | 1 | 1 | — | — | — | 1 |
Cryoglobulinemia | D003449 | EFO_0005846 | D89.1 | 1 | 1 | — | — | — | 1 |
Hypertension | D006973 | EFO_0000537 | I10 | 1 | 1 | — | — | — | 1 |
Pulmonary arterial hypertension | D000081029 | — | — | 1 | 1 | — | — | — | 1 |
Familial primary pulmonary hypertension | D065627 | — | I27.0 | 1 | 1 | — | — | — | 1 |
Ischemia | D007511 | EFO_0000556 | — | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 4 | — | — | — | 1 | 5 |
Osteomyelitis | D010019 | EFO_0003102 | M86 | 1 | — | — | — | 1 | 2 |
Recurrence | D012008 | — | — | 1 | — | — | — | 1 | 2 |
Therapeutic equivalency | D013810 | — | — | 2 | — | — | — | — | 2 |
Intestinal obstruction | D007415 | — | K56.60 | 2 | — | — | — | — | 2 |
Magnetic resonance imaging | D008279 | — | — | 1 | — | — | — | — | 1 |
Oral administration | D000284 | — | — | 1 | — | — | — | — | 1 |
Pharmacokinetics | D010599 | — | — | 1 | — | — | — | — | 1 |
Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | 1 | — | — | — | — | 1 |
Vomiting | D014839 | — | R11.1 | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Psoriasis | D011565 | EFO_0000676 | L40 | — | — | — | — | 2 | 2 |
Inflammatory bowel diseases | D015212 | EFO_0003767 | — | — | — | — | — | 2 | 2 |
Brain neoplasms | D001932 | EFO_0003833 | C71 | — | — | — | — | 2 | 2 |
Systemic scleroderma | D012595 | EFO_0000717 | M34 | — | — | — | — | 1 | 1 |
Localized scleroderma | D012594 | EFO_1001361 | L94.0 | — | — | — | — | 1 | 1 |
Diffuse scleroderma | D045743 | EFO_0000404 | — | — | — | — | — | 1 | 1 |
Papillomavirus infections | D030361 | — | — | — | — | — | — | 1 | 1 |
Disease attributes | D020969 | — | — | — | — | — | — | 1 | 1 |
Esophageal neoplasms | D004938 | — | C15 | — | — | — | — | 1 | 1 |
Gastroparesis | D018589 | EFO_1000948 | K31.84 | — | — | — | — | 1 | 1 |
Drug common name | Sulfasalazine |
INN | sulfasalazine |
Description | Sulfasalazine is an azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position. It has a role as a non-steroidal anti-inflammatory drug, an antiinfective agent, a gastrointestinal drug, an EC 2.5.1.18 (glutathione transferase) inhibitor, a drug allergen and a ferroptosis inducer. It is a sulfonamide, a member of pyridines and a member of azobenzenes. It is functionally related to a sulfanilamide. |
Classification | Small molecule |
Drug class | antiarrhythmic/antianginal/antihypertensive agents, phthalazine like structure; anti-inflammatory agents (salicylic acid derivatives); antimicrobials (sulfonamides derivatives) |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | O=C(O)c1cc(/N=N/c2ccc(S(=O)(=O)Nc3ccccn3)cc2)ccc1O |
PDB | — |
CAS-ID | 599-79-1 |
RxCUI | — |
ChEMBL ID | CHEMBL421 |
ChEBI ID | 9334 |
PubChem CID | 5339 |
DrugBank | DB00795 |
UNII ID | 3XC8GUZ6CB (ChemIDplus, GSRS) |