Sulfamethoxazole
Bactrim, Gantanol, Septra, Sulfamethoxazole / Trimethoprim, Sulfatrim, Urobak (sulfamethoxazole) is a small molecule pharmaceutical. Sulfamethoxazole was first approved as Gantanol on 1982-01-01. It is used to treat bacterial infections, chlamydiaceae infections, chronic bronchitis, enterobacteriaceae infections, and mycoses amongst others in the USA.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Trade Name
FDA
EMA
Combinations
Bactrim, Septra, Sulfamethoxazole trimethoprim, Sulfatrim (discontinued: Azo gantanol, Bactrim, Cotrim, Cotrim d.s, Septra, Septra grape, Sulfamethoxazole trimethoprim, Sulfamethoxazole trimethoprim phenazopyridine, Sulfatrim, Sulfatrim-ss, Trimeth/sulfa, Uroplus, Uroplus ss)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Sulfamethoxazole
+
Trimethoprim
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| SEPTRA | Monarch Pharmaceuticals | N-017376 RX | 1982-01-01 | 1 products |
| SEPTRA DS | Monarch Pharmaceuticals | N-017376 RX | 1982-01-01 | 1 products |
| SULFATRIM PEDIATRIC | PAI Pharma | N-018615 RX | 1983-01-07 | 1 products |
| BACTRIM | Sun Pharmaceutical Industries | N-017377 RX | 1982-01-01 | 1 products, RLD |
| BACTRIM DS | Sun Pharmaceutical Industries | N-017377 RX | 1982-01-01 | 1 products, RLD, RS |
Show 14 discontinued
Phenazopyridine hydrochloride
+
Sulfamethoxazole
Sulfamethoxazole
Phenazopyridine hydrochloride
+
Sulfamethoxazole
+
Trimethoprim
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| SULFAMETHOXAZOLE AND TRIMETHOPRIM AND PHENAZOPYRIDINE HYDROCHLORIDE | Able Laboratories | N-021105 DISCN | 2001-06-26 | 1 products |
Hide discontinued
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| bactrim bactrim ds | New Drug Application | 2024-12-30 |
| bactrim ds | New Drug Application | 2024-07-25 |
| sulfamethox-tmp ds | ANDA | 2022-10-09 |
| sulfamethoxazole and trimethoprim | ANDA | 2025-03-26 |
| sulfamethoxazole and trimethoprim ds | ANDA | 2010-04-28 |
| sulfamethoxazole, and trimethoprim | ANDA | 2009-10-09 |
| sulfatrim | New Drug Application | 2025-03-06 |
Indications
FDA
EMA
Show 10 more
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01E: Sulfonamides and trimethoprim antibacterials for systemic use
— J01EC: Intermediate-acting sulfonamides
— J01EC01: Sulfamethoxazole
— J01EE: Combinations of sulfonamides and trimethoprim, incl. derivatives
— J01EE01: Sulfamethoxazole and trimethoprim
— J04: Antimycobacterials
— J04A: Drugs for treatment of tuberculosis
— J04AM: Combinations of drugs for treatment of tuberculosis
— J04AM08: Isoniazid, sulfamethoxazole, trimethoprim and pyridoxine
HCPCS
Code | Description |
|---|---|
| S0039 | Injection, sulfamethoxazole and trimethoprim, 10 ml |
Clinical
Clinical Trials
247 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infections | D007239 | EFO_0000544 | — | 3 | 16 | 17 | 19 | 20 | 71 |
| Communicable diseases | D003141 | — | — | 2 | 7 | 12 | 13 | 15 | 48 |
| Hiv infections | D015658 | EFO_0000764 | B20 | 4 | 8 | 18 | 5 | 11 | 43 |
| Pneumonia | D011014 | EFO_0003106 | J18 | 2 | 7 | 19 | 5 | 9 | 39 |
| Pneumocystis pneumonia | D011020 | EFO_0007448 | B59 | 3 | 7 | 14 | 5 | 8 | 34 |
| Urinary tract infections | D014552 | EFO_0003103 | N39.0 | 1 | 7 | 5 | 9 | 11 | 32 |
| Malaria | D008288 | EFO_0001068 | B54 | — | 1 | 9 | 1 | 3 | 14 |
| Acquired immunodeficiency syndrome | D000163 | EFO_0000765 | B20 | — | 1 | 3 | 3 | 3 | 10 |
| Abscess | D000038 | EFO_0003030 | — | — | — | 2 | 2 | 6 | 10 |
| Bacteremia | D016470 | EFO_0003033 | R78.81 | — | — | 3 | 1 | 3 | 7 |
Show 65 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Staphylococcal infections | D013203 | — | A49.01 | — | 5 | 5 | — | 6 | 15 |
| Bacterial infections | D001424 | — | A49 | 3 | 1 | 1 | — | 2 | 7 |
| Sepsis | D018805 | EFO_0001420 | A41.9 | — | 1 | 3 | — | 3 | 7 |
| Multiple myeloma | D009101 | — | C90.0 | 1 | 4 | 1 | — | — | 5 |
| Plasma cell neoplasms | D054219 | — | — | 1 | 4 | 1 | — | — | 5 |
| Syndrome | D013577 | — | — | 2 | 2 | 1 | — | 1 | 5 |
| Neoplasms | D009369 | — | C80 | 3 | 2 | 1 | — | — | 4 |
| Fibrosis | D005355 | — | — | — | 2 | 2 | — | — | 4 |
| Kidney diseases | D007674 | EFO_0003086 | N08 | 2 | 2 | 1 | — | 1 | 4 |
| Lung diseases | D008171 | EFO_0003818 | J98.4 | — | 1 | 2 | — | — | 2 |
Show 38 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Staphylococcus aureus | D013211 | NCBITaxon_1280 | — | — | 2 | — | — | 4 | 6 |
| Lymphoma | D008223 | — | C85.9 | 1 | 4 | — | — | 1 | 5 |
| Leukemia | D007938 | — | C95 | 3 | 3 | — | — | — | 4 |
| Infectious arthritis | D001170 | EFO_1001351 | M00 | — | 1 | — | — | 2 | 3 |
| Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | C91.0 | 2 | 2 | — | — | — | 3 |
| Lymphoid leukemia | D007945 | — | C91 | 2 | 2 | — | — | — | 3 |
| Cellulitis | D002481 | EFO_0003035 | L03.90 | — | 1 | — | — | 2 | 3 |
| Cystic fibrosis | D003550 | EFO_0000390 | E84 | — | 3 | — | — | — | 3 |
| Disease progression | D018450 | — | — | 1 | 1 | — | — | 2 | 3 |
| Sinusitis | D012852 | EFO_0007486 | J32 | — | 1 | — | — | 1 | 2 |
Show 26 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Prosthesis-related infections | D016459 | EFO_1001406 | — | 1 | — | — | — | 2 | 3 |
| Healthy volunteers/patients | — | — | — | 2 | — | — | — | — | 2 |
| Congenital microtia | D065817 | — | Q16.0 | 1 | — | — | — | — | 1 |
| Brain neoplasms | D001932 | EFO_0003833 | C71 | 1 | — | — | — | — | 1 |
| Glioblastoma | D005909 | EFO_0000515 | — | 1 | — | — | — | — | 1 |
| Astrocytoma | D001254 | EFO_0000271 | — | 1 | — | — | — | — | 1 |
| Macular degeneration | D008268 | EFO_0001365 | H35.30 | 1 | — | — | — | — | 1 |
| Geographic atrophy | D057092 | — | — | 1 | — | — | — | — | 1 |
| Atrophy | D001284 | — | — | 1 | — | — | — | — | 1 |
| Small cell carcinoma | D018288 | — | — | 1 | — | — | — | — | 1 |
Show 6 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Bronchitis | D001991 | — | J40 | — | — | — | — | 3 | 3 |
| Hypospadias | D007021 | EFO_0004209 | Q54 | — | — | — | — | 3 | 3 |
| Ulcer | D014456 | MPATH_579 | — | — | — | — | — | 2 | 2 |
| Surgical wound infection | D013530 | — | — | — | — | — | — | 2 | 2 |
| Retinal detachment | D012163 | EFO_0005773 | H33.2 | — | — | — | — | 1 | 1 |
| Aortic dissection | D000784 | — | I71.0 | — | — | — | — | 1 | 1 |
| Long qt syndrome | D008133 | HP_0001657 | I45.81 | — | — | — | — | 1 | 1 |
| Delirium | D003693 | — | R41.0 | — | — | — | — | 1 | 1 |
| Torsades de pointes | D016171 | EFO_0005307 | I47.21 | — | — | — | — | 1 | 1 |
| Whooping cough | D014917 | EFO_0000650 | A37 | — | — | — | — | 1 | 1 |
Show 30 more
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Sulfamethoxazole |
| INN | sulfamethoxazole |
| Description | Sulfamethoxazole is an isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position. It has a role as an antibacterial agent, an antiinfective agent, an epitope, an EC 2.5.1.15 (dihydropteroate synthase) inhibitor, an antimicrobial agent, a P450 inhibitor, an EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor, an environmental contaminant, a xenobiotic and a drug allergen. It is a sulfonamide, a member of isoxazoles, a substituted aniline and a sulfonamide antibiotic. It is functionally related to a sulfanilamide. |
| Classification | Small molecule |
| Drug class | antimicrobials (sulfonamides derivatives) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1 |
Identifiers
| PDB | — |
| CAS-ID | 723-46-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL443 |
| ChEBI ID | 9332 |
| PubChem CID | 5329 |
| DrugBank | DB01015 |
| UNII ID | JE42381TNV (ChemIDplus, GSRS) |
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
₣
No data
Estimated US medical usage
Sulfamethoxazole
Total medical expenditures per year (USD, in millions)
Mock data
Subscribe for the real data
Subscribe for the real data
Number of persons purchased
Mock data
Subscribe for the real data
Subscribe for the real data
Number of purchases
Mock data
Subscribe for the real data
Subscribe for the real data
Refill frequency
Mock data
Subscribe for the real data
Subscribe for the real data
Price per prescription (USD)
Mock data
Subscribe for the real data
Subscribe for the real data
Sulfamethoxazole
+
Trimethoprim
Total medical expenditures per year (USD, in millions)
Mock data
Subscribe for the real data
Subscribe for the real data
Number of persons purchased
Mock data
Subscribe for the real data
Subscribe for the real data
Number of purchases
Mock data
Subscribe for the real data
Subscribe for the real data
Refill frequency
Mock data
Subscribe for the real data
Subscribe for the real data
Price per prescription (USD)
Mock data
Subscribe for the real data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 59,001 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
42,513 adverse events reported
View more details
© 2020-2025 Collaborative Drug Discovery Inc. (CDD) | Terms of Use