Sucralose
Sucralose is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
166 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Epilepsy | D004827 | EFO_0000474 | G40.9 | — | 5 | 4 | — | — | 9 |
| Myoclonic epilepsies | D004831 | EFO_1001900 | G40.4 | — | 1 | 2 | — | — | 3 |
| Infantile spasms | D013036 | EFO_1000643 | G40.82 | — | — | 2 | — | — | 2 |
| Tuberous sclerosis | D014402 | — | Q85.1 | — | — | 2 | — | — | 2 |
| Seizures | D012640 | — | G40.4 | — | — | 2 | — | — | 2 |
| Lennox gastaut syndrome | D065768 | — | G40.81 | — | — | 2 | — | — | 2 |
| Rett syndrome | D015518 | Orphanet_778 | F84.2 | — | — | 1 | — | — | 1 |
| Narcolepsy | D009290 | EFO_0000614 | G47.4 | — | — | 1 | — | — | 1 |
| Cataplexy | D002385 | — | — | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Autism spectrum disorder | D000067877 | — | F84.0 | — | 2 | — | — | — | 2 |
| Schizophrenia | D012559 | EFO_0000692 | F20 | — | 2 | — | — | — | 2 |
| Psychotic disorders | D011618 | — | F20.81 | — | 1 | — | — | — | 1 |
| Mental disorders | D001523 | EFO_0000677 | F91.9 | — | 1 | — | — | — | 1 |
| Autistic disorder | D001321 | EFO_0003758 | F84.0 | — | 1 | — | — | — | 1 |
| Pervasive child development disorders | D002659 | EFO_0003756 | F84 | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Sucralose |
| INN | _ |
| Description | Sucralose is a disaccharide derivative consisting of 4-chloro-4-deoxy-alpha-D-galactopyranose and 1,6-dichloro-1,6-dideoxy-beta-D-fructofuranose units linked by a glycosidic bond. It has a role as an environmental contaminant, a xenobiotic and a sweetening agent. It is a disaccharide derivative and an organochlorine compound. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | OC[C@@H]1O[C@H](O[C@]2(CCl)O[C@H](CCl)[C@@H](O)[C@@H]2O)[C@@H](O)[C@@H](O)[C@H]1Cl |
Identifiers
| PDB | — |
| CAS-ID | 56038-13-2 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2107529 |
| ChEBI ID | — |
| PubChem CID | 71485 |
| DrugBank | — |
| UNII ID | 96K6UQ3ZD4 (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
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Safety
Black-box Warning
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Adverse Events
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34 adverse events reported
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