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AboutPricing
Drug ReportsStreptomycin
Streptomycin
Streptomycin (streptomycin) is a small molecule pharmaceutical. Streptomycin was first approved as Streptomycin sulfate on 1982-01-01. It is used to treat bacterial endocarditis, brucellosis, chancroid, escherichia coli infections, and granuloma inguinale amongst others in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
urogenital diseasesD000091642
cardiovascular diseasesD002318
skin and connective tissue diseasesD017437
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
Brand Name
Status
Last Update
streptomycinANDA2023-08-15
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
urinary tract infectionsEFO_0003103D014552N39.0
escherichia coli infectionsEFO_1001318D004927B96.20
streptococcal infectionsEFO_1001476D013290—
bacterial endocarditisEFO_1000830D004697—
proteus infectionsEFO_1001130D011512—
brucellosisEFO_0007185D002006A23
plagueEFO_0007481D010930A20
klebsiella infectionsEFO_1001353D007710—
mycobacterium infections—D009164A31.9
tularemiaEFO_1001444D014406A21
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Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
A: Alimentary tract and metabolism drugs
— A07: Antidiarrheals, intestinal antiinflammatory/antiinfective agents
— A07A: Intestinal antiinfectives
— A07AA: Antibiotics, intestinal
— A07AA04: Streptomycin
— A07AA54: Streptomycin, combinations
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01G: Aminoglycoside antibacterials
— J01GA: Streptomycins
— J01GA01: Streptomycin
— J04: Antimycobacterials
— J04A: Drugs for treatment of tuberculosis
— J04AM: Combinations of drugs for treatment of tuberculosis
— J04AM01: Streptomycin and isoniazid
HCPCS
Code
Description
J3000
Injection, streptomycin, up to 1 gm
Clinical
Clinical Trials
32 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
TuberculosisD014376EFO_0000774A15-A192312411
Pulmonary tuberculosisD014397EFO_1000049A15—1—135
Multidrug-resistant tuberculosisD018088EFO_0007381——1—1—2
Stem cell researchD057905—————2—2
KeloidD007627EFO_0004212L91.0———2—2
ReinfectionD000084063—————1—1
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
InfectionsD007239EFO_0000544——21—13
Buruli ulcerD054312EFO_1001281A31.1—22—13
Mycobacterium infectionsD009164—A31.9—21—13
Hiv infectionsD015658EFO_0000764B20—11—12
PlagueD010930EFO_0007481A20—12——2
Mycobacterium ulceransD019911———11—12
Acquired immunodeficiency syndromeD000163EFO_0000765B20—11——1
PoliomyelitisD011051EFO_0007450A80——1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Mycobacterium avium-intracellulare infectionD015270EFO_0007386——1———1
DengueD003715—A90—1———1
FrailtyD000073496—R53.111———1
Human influenzaD007251EFO_0007328J11.111———1
Haemophilus influenzaeD006193NCBITaxon_727—11———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
OsteomyelitisD010019EFO_0003102M861————1
Healthy volunteers/patients———1————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
PneumoniaD011014EFO_0003106—————11
Klebsiella infectionsD007710EFO_1001353—————11
Diabetes mellitusD003920HP_0000819E08-E13————11
Gestational diabetesD016640HP_0009800O24.4————11
Inborn errors metabolismD008661——————11
Peripheral nervous system diseasesD010523HP_0009830G64————11
Diabetic neuropathiesD003929EFO_1000783—————11
Spontaneous abortionD000022EFO_1001255O00.1————11
VitiligoD014820EFO_0004208L80————11
Colorectal neoplasmsD015179——————11
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameStreptomycin
INNstreptomycin
Description
Streptomycin is a amino cyclitol glycoside that consists of streptidine having a disaccharyl moiety attached at the 4-position. The parent of the streptomycin class It has a role as an antimicrobial agent, an antimicrobial drug, an antibacterial drug, a protein synthesis inhibitor, a bacterial metabolite and an antifungal agrochemical. It is an antibiotic antifungal drug, an antibiotic fungicide and a member of streptomycins. It is functionally related to a streptidine. It is a conjugate base of a streptomycin(3+).
Classification
Small molecule
Drug classantibiotics (Streptomyces strain)
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CN[C@@H]1[C@H](O[C@H]2[C@H](O[C@@H]3[C@@H](N=C(N)N)[C@H](O)[C@@H](N=C(N)N)[C@H](O)[C@H]3O)O[C@@H](C)[C@]2(O)C=O)O[C@@H](CO)[C@H](O)[C@H]1O
Identifiers
PDB—
CAS-ID57-92-1
RxCUI—
ChEMBL IDCHEMBL372795
ChEBI ID17076
PubChem CID19649
DrugBankDB01082
UNII IDY45QSO73OB (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 500,845 documents
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Safety
Black-box Warning
Black-box warning for: Streptomycin
Adverse Events
Top Adverse Reactions
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776 adverse events reported
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