Spartalizumab
Spartalizumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against programmed cell death protein 1.
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Commercial
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Clinical
Clinical Trials
295 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Melanoma | D008545 | — | — | 5 | 2 | — | — | — | 5 |
| Neoplasms | D009369 | — | C80 | 5 | 4 | — | — | — | 5 |
| Squamous cell carcinoma of head and neck | D000077195 | — | — | — | 1 | — | — | — | 1 |
| Carcinoma | D002277 | — | C80.0 | 1 | 1 | — | — | — | 1 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | 1 | — | — | — | 1 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 1 | 1 | — | — | — | 1 |
| Head and neck neoplasms | D006258 | — | — | 1 | 1 | — | — | — | 1 |
| Lung neoplasms | D008175 | — | C34.90 | 1 | 1 | — | — | — | 1 |
| Sarcoma | D012509 | — | — | 1 | 1 | — | — | — | 1 |
| Lymphoma | D008223 | — | C85.9 | 1 | 1 | — | — | — | 1 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Glioblastoma | D005909 | EFO_0000515 | — | 2 | — | — | — | — | 2 |
| Cutaneous malignant melanoma | D000096142 | — | — | 2 | — | — | — | — | 2 |
| Neoplasms by histologic type | D009370 | — | — | 1 | — | — | — | — | 1 |
| Neoplasms by site | D009371 | — | — | 1 | — | — | — | — | 1 |
| Brain neoplasms | D001932 | EFO_0003833 | C71 | 1 | — | — | — | — | 1 |
| Gliosarcoma | D018316 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Spartalizumab |
| INN | spartalizumab |
| Description | Spartalizumab (INN; development code PDR001) is a monoclonal antibody and checkpoint inhibitor that is being investigated for melanoma.
|
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297831 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | QOG25L6Z8Z (ChemIDplus, GSRS) |
Target
Agency Approved
PDCD1
PDCD1
Alternate
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Variants
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Financial
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PubMed Central
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Additional graphs summarizing 2,516 documents
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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313 adverse events reported
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