Somatostatin
Somatostatin is a protein pharmaceutical. It is currently being investigated in clinical studies.
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Drug Products
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Abbreviated New Drug Application (ANDA)
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Clinical
Clinical Trials
359 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Acromegaly | D000172 | — | — | 1 | — | 2 | 3 | — | 6 |
| Central nervous system neoplasms | D016543 | — | — | 1 | — | — | 1 | — | 2 |
| Meningioma | D008579 | EFO_0003098 | D32.9 | — | 1 | — | 1 | — | 2 |
| Pituitary neoplasms | D010911 | — | — | — | — | — | 2 | — | 2 |
| Medulloblastoma | D008527 | — | — | — | — | — | 1 | — | 1 |
| Paraganglioma | D010235 | — | — | — | — | — | 1 | — | 1 |
| Hemangioblastoma | D018325 | — | — | — | — | — | 1 | — | 1 |
| Olfactory esthesioneuroblastoma | D018304 | EFO_1000407 | — | — | — | — | 1 | — | 1 |
| Brain neoplasms | D001932 | EFO_0003833 | C71 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Carcinoid tumor | D002276 | — | D3A.00 | 2 | — | 1 | — | — | 3 |
| Carcinoma | D002277 | — | C80.0 | — | — | 1 | — | — | 1 |
| Hepatocellular carcinoma | D006528 | — | C22.0 | — | — | 1 | — | — | 1 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neuroendocrine tumors | D018358 | EFO_1001901 | D3A.8 | — | 1 | — | — | 3 | 4 |
| Lung neoplasms | D008175 | — | C34.90 | 1 | 2 | — | — | — | 3 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | 1 | — | — | — | 2 |
| Neoplasms | D009369 | — | C80 | 1 | 1 | — | — | — | 2 |
| Prostatic neoplasms | D011471 | — | C61 | 1 | 1 | — | — | — | 2 |
| Small cell lung carcinoma | D055752 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Gastrointestinal neoplasms | D005770 | — | C26.9 | 1 | — | — | — | — | 1 |
| Lymphoma | D008223 | — | C85.9 | 1 | — | — | — | — | 1 |
| Melanoma | D008545 | — | — | 1 | — | — | — | — | 1 |
| Paraneoplastic syndromes | D010257 | — | — | 1 | — | — | — | — | 1 |
| Nervous system neoplasms | D009423 | — | — | 1 | — | — | — | — | 1 |
| Islet cell adenoma | D007516 | EFO_0007331 | D13.7 | 1 | — | — | — | — | 1 |
| Malignant carcinoid syndrome | D008303 | — | E34.0 | 1 | — | — | — | — | 1 |
| Hypoglycemia | D007003 | — | E16.2 | 1 | — | — | — | — | 1 |
| Congenital hyperinsulinism | D044903 | — | — | 1 | — | — | — | — | 1 |
| Nesidioblastosis | D046768 | EFO_0007318 | E16.9 | 1 | — | — | — | — | 1 |
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Somatostatin |
| INN | somatostatin |
| Description | SOMATOSTATIN |
| Classification | Protein |
| Drug class | growth hormone derivatives; enzyme inhibitors: antihyperlipidemics (HMG-CoA inhibitors) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C[C@H](N)C(=O)NCC(=O)N[C@H]1CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O |
Identifiers
| PDB | — |
| CAS-ID | 38916-34-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1823872 |
| ChEBI ID | 64628 |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 6E20216Q0L (ChemIDplus, GSRS) |
Target
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Safety
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118 adverse events reported
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