Solithromycin
Solithromycin is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Clinical
Clinical Trials
11 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pneumonia | D011014 | EFO_0003106 | — | — | 2 | 3 | — | — | 4 |
| Community-acquired infections | D017714 | — | — | — | 2 | 3 | — | — | 4 |
| Bacterial pneumonia | D018410 | EFO_1001272 | J15.9 | — | 2 | 3 | — | — | 4 |
| Gonorrhea | D006069 | DOID_7551 | A54 | 1 | 1 | 1 | — | — | 3 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | — | 1 | — | — | — | 1 |
| Lung diseases | D008171 | HP_0002088 | J98.4 | — | 1 | — | — | — | 1 |
| Obstructive lung diseases | D008173 | HP_0006536 | — | — | 1 | — | — | — | 1 |
| Non-alcoholic fatty liver disease | D065626 | EFO_0003095 | K75.81 | — | 1 | — | — | — | 1 |
| Fatty liver | D005234 | EFO_0003934 | — | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infections | D007239 | EFO_0000544 | — | 2 | — | — | — | — | 2 |
| Bacterial infections | D001424 | — | A49 | 2 | — | — | — | — | 2 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Solithromycin |
| INN | solithromycin |
| Description | Solithromycin (trade name Solithera) is a ketolide antibiotic undergoing clinical development for the treatment of community-acquired pneumonia and other infections.
|
| Classification | Small molecule |
| Drug class | antibiotics (Streptomyces strain) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC[C@H]1OC(=O)[C@@](C)(F)C(=O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(OC)C[C@@H](C)C(=O)[C@H](C)[C@H]2N(CCCCn3cc(-c4cccc(N)c4)nn3)C(=O)O[C@]12C |
Identifiers
| PDB | — |
| CAS-ID | 760981-83-7 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1232510 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB09308 |
| UNII ID | 9U1ETH79CK (ChemIDplus, GSRS) |
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Safety
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Adverse Events
0 adverse events reported
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