Sitafloxacin
Sitafloxacin is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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New Drug Application (NDA)
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Abbreviated New Drug Application (ANDA)
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Clinical
Clinical Trials
8 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Bronchiectasis | D001987 | — | J47 | — | — | — | 1 | — | 1 |
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | — | — | — | 1 | — | 1 |
| Disease progression | D018450 | — | — | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pulmonary tuberculosis | D014397 | EFO_1000049 | A15 | — | — | 3 | — | — | 3 |
| Escherichia coli infections | D004927 | EFO_1001318 | B96.20 | — | 2 | 1 | — | — | 2 |
| Kidney transplantation | D016030 | — | — | — | 1 | 1 | — | — | 1 |
| Urinary tract infections | D014552 | EFO_0003103 | N39.0 | — | 1 | 1 | — | — | 1 |
| Klebsiella infections | D007710 | EFO_1001353 | — | — | 1 | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infections | D007239 | EFO_0000544 | — | — | 1 | — | — | — | 1 |
| Pyelonephritis | D011704 | EFO_1001141 | N10-N16 | — | 1 | — | — | — | 1 |
| Mycobacterium infections | D009164 | — | A31.9 | — | 1 | — | — | — | 1 |
| Mycobacterium | D009161 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Sitafloxacin |
| INN | sitafloxacin |
| Description | Sitafloxacin is a member of quinolines, a quinolone antibiotic and a fluoroquinolone antibiotic. |
| Classification | Small molecule |
| Drug class | antibacterials (quinolone derivatives) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | N[C@@H]1CN(c2c(F)cc3c(=O)c(C(=O)O)cn([C@@H]4C[C@@H]4F)c3c2Cl)CC12CC2 |
Identifiers
| PDB | — |
| CAS-ID | 127254-12-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL108821 |
| ChEBI ID | — |
| PubChem CID | 461399 |
| DrugBank | — |
| UNII ID | 3GJC60U4Q8 (ChemIDplus, GSRS) |
Target
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Trends
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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106 adverse events reported
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