Sintilimab
Sintilimab is an antibody pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
597 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Carcinoma | D002277 | — | C80.0 | — | 1 | 1 | — | — | 1 |
| Hepatocellular carcinoma | D006528 | — | C22.0 | — | 1 | 1 | — | — | 1 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | — | 1 | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| T-cell lymphoma peripheral | D016411 | — | — | 1 | 13 | — | — | — | 14 |
| T-cell lymphoma | D016399 | — | — | 1 | 13 | — | — | — | 14 |
| Squamous cell carcinoma of head and neck | D000077195 | — | — | 1 | 12 | — | — | — | 12 |
| Cholangiocarcinoma | D018281 | — | C22.1 | 2 | 10 | — | — | 2 | 12 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 4 | 9 | — | — | 2 | 11 |
| Drug therapy | D004358 | — | — | 1 | 5 | — | — | 2 | 8 |
| Uterine cervical neoplasms | D002583 | — | — | 2 | 7 | — | — | 1 | 8 |
| Biliary tract neoplasms | D001661 | — | C24.9 | 1 | 6 | — | — | 1 | 7 |
| Healthy volunteers/patients | — | — | — | 4 | 4 | — | — | — | 6 |
| Chemoradiotherapy | D059248 | — | — | 1 | 5 | — | — | 1 | 6 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Osteosarcoma | D012516 | — | — | 1 | — | — | — | — | 1 |
| Adenocarcinoma of lung | D000077192 | — | — | 1 | — | — | — | — | 1 |
| Drug-related side effects and adverse reactions | D064420 | — | T88.7 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Liver diseases | D008107 | EFO_0001421 | K70-K77 | — | — | — | — | 2 | 2 |
| Hepatitis b | D006509 | — | — | — | — | — | — | 2 | 2 |
| Chronic hepatitis b | D019694 | EFO_0004239 | B18.1 | — | — | — | — | 2 | 2 |
| Hepatitis | D006505 | — | K75.9 | — | — | — | — | 2 | 2 |
| Chronic hepatitis | D006521 | — | K73.9 | — | — | — | — | 2 | 2 |
| Catheter ablation | D017115 | — | — | — | — | — | — | 2 | 2 |
| Female genital neoplasms | D005833 | — | — | — | — | — | — | 1 | 1 |
| Abdominal neoplasms | D000008 | — | — | — | — | — | — | 1 | 1 |
| Meningioma | D008579 | EFO_0003098 | D32.9 | — | — | — | — | 1 | 1 |
| Venous thrombosis | D020246 | — | I82.40 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Sintilimab |
| INN | sintilimab |
| Description | Sintilimab, sold under the brand Tyvyt among others, is a medication used to treat Hodgkin's disease, and has been approved in China.
|
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 2072873-06-2 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297829 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB15765 |
| UNII ID | 8FU7FQ8UPK (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
PubMed Central
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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424 adverse events reported
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