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Drug ReportsSintilimab
Sintilimab
Sintilimab is an antibody pharmaceutical. It is currently being investigated in clinical studies.
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Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
690 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Non-small-cell lung carcinomaD002289——1350151883
Stomach neoplasmsD013274EFO_0003897C16116171675
Lung neoplasmsD008175—C34.9093871758
AdenocarcinomaD000230——42841235
LymphomaD008223—C85.911511—18
Breast neoplasmsD001943EFO_0003869C50—51118
Hodgkin diseaseD006689—C81—31116
Triple negative breast neoplasmsD064726———5—1—6
Thyroid neoplasmsD013964EFO_0003841——1—1—2
Thyroid diseasesD013959—E00-E07—1—1—2
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
CarcinomaD002277—C80.076814—31114
Hepatocellular carcinomaD006528—C22.0126012—38112
Liver neoplasmsD008113EFO_1001513C22.010499—2787
Colorectal neoplasmsD015179——7386—956
NeoplasmsD009369—C8025333—556
Squamous cell carcinomaD002294——1228—535
Esophageal squamous cell carcinomaD000077277——2208—534
ImmunotherapyD007167——5201—729
Neoplasm metastasisD009362EFO_0009708—3162——20
Esophageal neoplasmsD004938—C154133—119
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Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
CholangiocarcinomaD018281—C22.1211——213
Pancreatic neoplasmsD010190EFO_0003860C25410——212
T-cell lymphoma peripheralD016411——19———10
T-cell lymphomaD016399——18———9
Drug therapyD004358——25——28
Uterine cervical neoplasmsD002583——17——18
Biliary tract neoplasmsD001661—C24.916——17
Healthy volunteers/patients———44———6
Large b-cell lymphoma diffuseD016403—C83.315———6
Extranodal nk-t-cell lymphomaD054391—C86.0—4——15
Show 57 more
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Drug-related side effects and adverse reactionsD064420—T88.71———12
OsteosarcomaD012516——1————1
Adenocarcinoma of lungD000077192——1————1
Meningeal carcinomatosisD055756EFO_1001012—1————1
Gastrointestinal stromal tumorsD046152EFO_0000505C49.A1————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Liver diseasesD008107EFO_0001421K70-K77————22
Chronic hepatitis bD019694EFO_0004239B18.1————22
Catheter ablationD017115——————22
Female genital neoplasmsD005833——————11
Abdominal neoplasmsD000008——————11
MeningiomaD008579EFO_0003098D32.9————11
Venous thrombosisD020246—I82.40————11
Hemophagocytic lymphohistiocytosisD051359—D76.1————11
AnalgesiaD000698——————11
AgnosiaD000377EFO_0007136F88————11
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameSintilimab
INNsintilimab
Description
Sintilimab, sold under the brand Tyvyt among others, is a medication used to treat Hodgkin's disease, and has been approved in China.
Classification
Antibody
Drug classmonoclonal antibodies
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Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID2072873-06-2
RxCUI—
ChEMBL IDCHEMBL4297829
ChEBI ID—
PubChem CID—
DrugBankDB15765
UNII ID8FU7FQ8UPK (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 7,896 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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703 adverse events reported
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