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Drug ReportsSevoflurane
Sevoflurane
Sevoflurane, Sojourn, Ultane (sevoflurane) is a small molecule pharmaceutical. Sevoflurane was first approved as Ultane on 1995-06-07. It is used to treat pain in the USA.
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Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
signs and symptoms pathological conditionsD013568
psychological phenomenaD011579
musculoskeletal and neural physiological phenomenaD055687
Trade Name
FDA
EMA
Sevoflurane, Sojourn, Ultane
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Sevoflurane
Tradename
Company
Number
Date
Products
ULTANEAbbVieN-020478 RX1995-06-07
1 products, RLD, RS
Labels
FDA
EMA
Brand Name
Status
Last Update
sevofluraneANDA2024-09-13
sevoflurane bostonbioANDA2020-09-09
sojournANDA2024-06-26
ultaneNew Drug Application2022-08-18
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
painEFO_0003843D010146R52
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
N: Nervous system drugs
N01: Anesthetics
N01A: Anesthetics, general
N01AB: Halogenated hydrocarbons, general anesthetics
N01AB08: Sevoflurane
HCPCS
No data
Clinical
Clinical Trials
1080 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
AnesthesiaD00075878143176133
Emergence deliriumD000071257434304987
Postoperative painD010149G89.18334164670
DeliriumD003693R41.0112194164
General anesthesiaD000768125114563
Psychomotor agitationD011595322201844
Cognitive dysfunctionD060825HP_0001268G31.842192233
Respiratory aspirationD053120EFO_10018391132631
Postoperative cognitive complicationsD0000796902171625
Heart diseasesD006331EFO_0003777I51.9327820
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
AnalgesiaD00069821012
DepressionD003863F33.9178
Respiratory insufficiencyD012131HP_0002093J96.9235
Neurotoxicity syndromesD020258G92145
Intratracheal intubationD007442145
Liver diseasesD008107HP_0002910K70-K772124
Substance-related disordersD019966EFO_0003890F132124
Kidney transplantationD0160301124
Only childD009863123
Aortic valve insufficiencyD001022EFO_0007148213
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Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Intraocular pressureD007429123
Arteriovenous fistulaD001164Q27.311
GlaucomaD005901EFO_0000516H4011
Respiratory tract diseasesD01214011
Respiration disordersD012120J00-J9911
Tympanic membrane perforationD018058H7211
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
ElectroencephalographyD00456966
Thoracic surgical proceduresD01961655
HypospadiasD007021EFO_0004209Q5455
Epidural anesthesiaD00076744
Spinal diseasesD013122M45-M4944
Sleep wake disordersD012893G4744
HysterectomyD007044EFO_000388133
HemiarthroplastyD06278533
PharyngitisD010612R07.033
Operative surgical proceduresD01351433
Show 234 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameSevoflurane
INNsevoflurane
Description
Sevoflurane is an ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups. It has a role as an inhalation anaesthetic, a platelet aggregation inhibitor and a central nervous system depressant. It is an organofluorine compound and an ether. It is functionally related to a 2-methoxypropane.
Classification
Small molecule
Drug classgeneral inhalation anesthetics (halogenated alkane derivatives)
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
FCOC(C(F)(F)F)C(F)(F)F
Identifiers
PDB
CAS-ID28523-86-6
RxCUI
ChEMBL IDCHEMBL1200694
ChEBI ID9130
PubChem CID5206
DrugBankDB01236
UNII ID38LVP0K73A (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
£
Sevoflurane AbbVie
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Estimated US medical usage
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 28,534 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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6,820 adverse events reported
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