Brand Name | Status | Last Update |
---|---|---|
sevoflurane | ANDA | 2024-09-13 |
sevoflurane bostonbio | ANDA | 2020-09-09 |
sojourn | ANDA | 2024-06-26 |
ultane | New Drug Application | 2022-08-18 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
pain | EFO_0003843 | D010146 | R52 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Anesthesia | D000758 | — | — | 7 | 8 | 14 | 31 | 76 | 133 |
Emergence delirium | D000071257 | — | — | 4 | 3 | 4 | 30 | 49 | 87 |
Postoperative pain | D010149 | — | G89.18 | 3 | 3 | 4 | 16 | 46 | 70 |
Delirium | D003693 | — | R41.0 | 1 | 1 | 2 | 19 | 41 | 64 |
General anesthesia | D000768 | — | — | 1 | 2 | 5 | 11 | 45 | 63 |
Psychomotor agitation | D011595 | — | — | 3 | 2 | 2 | 20 | 18 | 44 |
Cognitive dysfunction | D060825 | HP_0001268 | G31.84 | 2 | 1 | — | 9 | 22 | 33 |
Respiratory aspiration | D053120 | EFO_1001839 | — | — | 1 | 1 | 3 | 26 | 31 |
Postoperative cognitive complications | D000079690 | — | — | 2 | 1 | — | 7 | 16 | 25 |
Heart diseases | D006331 | EFO_0003777 | I51.9 | 3 | 2 | — | 7 | 8 | 20 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Analgesia | D000698 | — | — | — | — | 2 | — | 10 | 12 |
Depression | D003863 | — | F33.9 | — | — | 1 | — | 7 | 8 |
Respiratory insufficiency | D012131 | HP_0002093 | J96.9 | — | — | 2 | — | 3 | 5 |
Neurotoxicity syndromes | D020258 | — | G92 | — | — | 1 | — | 4 | 5 |
Intratracheal intubation | D007442 | — | — | — | — | 1 | — | 4 | 5 |
Liver diseases | D008107 | HP_0002910 | K70-K77 | — | 2 | 1 | — | 2 | 4 |
Substance-related disorders | D019966 | EFO_0003890 | F13 | — | 2 | 1 | — | 2 | 4 |
Kidney transplantation | D016030 | — | — | — | 1 | 1 | — | 2 | 4 |
Only child | D009863 | — | — | — | — | 1 | — | 2 | 3 |
Aortic valve insufficiency | D001022 | EFO_0007148 | — | 2 | — | 1 | — | — | 3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Wounds and injuries | D014947 | — | T14.8 | 1 | 3 | — | — | 5 | 8 |
Phimosis | D010688 | EFO_1001104 | N47.1 | 1 | 1 | — | — | 1 | 3 |
Lung injury | D055370 | — | S27.30 | 1 | 1 | — | — | 2 | 3 |
Down syndrome | D004314 | EFO_0001064 | Q90 | — | 1 | — | — | 2 | 3 |
Atrial fibrillation | D001281 | EFO_0000275 | I48.0 | 1 | 1 | — | — | 2 | 3 |
Opioid-related disorders | D009293 | EFO_0005611 | F11 | — | 1 | — | — | 2 | 3 |
Paraphimosis | D010263 | EFO_1001086 | N47.2 | 1 | 1 | — | — | — | 2 |
Balanitis | D001446 | EFO_1000833 | N48.1 | 1 | 1 | — | — | — | 2 |
Radical mastectomy | D015409 | — | — | 1 | 1 | — | — | — | 1 |
Gastric bypass | D015390 | EFO_0005244 | — | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Intraocular pressure | D007429 | — | — | 1 | — | — | — | 2 | 3 |
Arteriovenous fistula | D001164 | — | Q27.3 | 1 | — | — | — | — | 1 |
Glaucoma | D005901 | EFO_0000516 | H40 | 1 | — | — | — | — | 1 |
Respiratory tract diseases | D012140 | — | — | 1 | — | — | — | — | 1 |
Respiration disorders | D012120 | — | J00-J99 | 1 | — | — | — | — | 1 |
Tympanic membrane perforation | D018058 | — | H72 | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Electroencephalography | D004569 | — | — | — | — | — | — | 6 | 6 |
Thoracic surgical procedures | D019616 | — | — | — | — | — | — | 5 | 5 |
Hypospadias | D007021 | EFO_0004209 | Q54 | — | — | — | — | 5 | 5 |
Epidural anesthesia | D000767 | — | — | — | — | — | — | 4 | 4 |
Spinal diseases | D013122 | — | M45-M49 | — | — | — | — | 4 | 4 |
Sleep wake disorders | D012893 | — | G47 | — | — | — | — | 4 | 4 |
Hysterectomy | D007044 | EFO_0003881 | — | — | — | — | — | 3 | 3 |
Hemiarthroplasty | D062785 | — | — | — | — | — | — | 3 | 3 |
Pharyngitis | D010612 | — | R07.0 | — | — | — | — | 3 | 3 |
Operative surgical procedures | D013514 | — | — | — | — | — | — | 3 | 3 |
Drug common name | Sevoflurane |
INN | sevoflurane |
Description | Sevoflurane is an ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups. It has a role as an inhalation anaesthetic, a platelet aggregation inhibitor and a central nervous system depressant. It is an organofluorine compound and an ether. It is functionally related to a 2-methoxypropane. |
Classification | Small molecule |
Drug class | general inhalation anesthetics (halogenated alkane derivatives) |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | FCOC(C(F)(F)F)C(F)(F)F |
PDB | — |
CAS-ID | 28523-86-6 |
RxCUI | — |
ChEMBL ID | CHEMBL1200694 |
ChEBI ID | 9130 |
PubChem CID | 5206 |
DrugBank | DB01236 |
UNII ID | 38LVP0K73A (ChemIDplus, GSRS) |