Sepetaprost
Sepetaprost is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target prostaglandin F2-alpha receptor.
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Events Timeline
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YTD
1Y
2Y
5Y
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Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
8 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hypertension | D006973 | EFO_0000537 | I10 | 1 | 3 | 2 | — | — | 6 |
| Ocular hypertension | D009798 | EFO_1001069 | H40.0 | 1 | 3 | 2 | — | — | 6 |
| Glaucoma | D005901 | EFO_0000516 | H40 | 1 | 3 | 2 | — | — | 6 |
| Open-angle glaucoma | D005902 | EFO_0004190 | H40.1 | 1 | 3 | 2 | — | — | 6 |
Indications Phases 2
No data
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Sepetaprost |
| INN | sepetaprost |
| Description | Sepetaprost is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target prostaglandin F2-alpha receptor. |
| Classification | Small molecule |
| Drug class | prostaglandins |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(C)OC(=O)CCC[C@H]1CC[C@H]2[C@H](C[C@@H](O)[C@@H]2/C=C/[C@@H](O)COc2cc(F)ccc2F)OC1 |
Identifiers
| PDB | — |
| CAS-ID | 1262873-06-2 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297633 |
| ChEBI ID | — |
| PubChem CID | 50902259 |
| DrugBank | DB12043 |
| UNII ID | 79O7855J4G (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
PTGFR
PTGFR
Organism
Homo sapiens
Gene name
PTGFR
Gene synonyms
NCBI Gene ID
Protein name
prostaglandin F2-alpha receptor
Protein synonyms
FP prostanoid receptor, PGF receptor, PGF2 alpha receptor, prostaglandin receptor (2-alpha), Prostanoid FP receptor
Uniprot ID
Mouse ortholog
Ptgfr (19220)
prostaglandin F2-alpha receptor (P43117)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 21 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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