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AboutPricing
Drug ReportsScopolamine
Scopolamine
Scopolamine, Transderm Scop (scopolamine) is a small molecule pharmaceutical. Scopolamine was first approved as Transderm scop on 1982-01-01. It is used to treat colonic diseases, diverticulitis, dysentery, facial paralysis, and iridocyclitis amongst others in the USA. The pharmaceutical is active against muscarinic acetylcholine receptor M1 and muscarinic acetylcholine receptor M3. In addition, it is known to target muscarinic acetylcholine receptor M2, muscarinic acetylcholine receptor M4, and muscarinic acetylcholine receptor M5.
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Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
digestive system diseasesD004066
stomatognathic diseasesD009057
respiratory tract diseasesD012140
otorhinolaryngologic diseasesD010038
nervous system diseasesD009422
eye diseasesD005128
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
Scopolamine, Transderm scop
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Scopolamine
Tradename
Company
Number
Date
Products
TRANSDERM SCOPBaxterN-017874 RX1982-01-01
1 products, RLD
Labels
FDA
EMA
Brand Name
Status
Last Update
atenolol scopolamineunapproved drug other2014-10-15
donnatalunapproved drug other2024-12-05
donnatal extentabsunapproved drug other2011-10-17
kimiteunapproved drug other2018-12-12
phenobarbital, hyoscyamine sulfate, atropine sulfate and scopolamine hydrobromideunapproved drug other2023-01-10
phenobarbital, hyoscyamine sulfate, atropine sulfate, scopolamine hydrobromideunapproved drug other2023-01-12
phenohytrounapproved drug other2025-09-22
propranolol scopolamineunapproved drug other2014-10-15
quadrapaxunapproved drug other2011-09-13
scopolamineANDA2025-08-23
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Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
facial paralysis—D005158G51.0
colonic diseases—D003108—
diverticulitisEFO_1001460D004238K57
iridocyclitis—D015863H20
vasomotor rhinitisEFO_0007533D012223J30.0
dysenteryEFO_1001869D004403—
postencephalitic parkinson diseaseEFO_1001402D010301G21.3
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
A: Alimentary tract and metabolism drugs
— A04: Antiemetics and antinauseants
— A04A: Antiemetics and antinauseants
— A04AD: Other antiemetics in atc
— A04AD01: Scopolamine
— A04AD51: Scopolamine, combinations
N: Nervous system drugs
— N05: Psycholeptics
— N05C: Hypnotics and sedatives
— N05CM: Other hypnotics and sedatives in atc
— N05CM05: Scopolamine
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01F: Mydriatics and cycloplegics
— S01FA: Anticholinergic mydriatics and cycloplegics
— S01FA02: Scopolamine
HCPCS
No data
Clinical
Clinical Trials
438 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Chronic obstructive pulmonary diseaseD029424EFO_0000341J44.9——2——2
Lung diseasesD008171EFO_0003818J98.4——2——2
Obstructive lung diseasesD008173————2——2
Respiratory aspirationD053120EFO_1001839———1——1
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameScopolamine
INN—
Description
[(1S,5R)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl] (2S)-3-hydroxy-2-phenylpropanoate is a 3-hydroxy carboxylic acid.
Classification
Small molecule
Drug class Antimuscarinic Deliriant Antiemetic Amnestic
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CN1[C@H]2C[C@H](OC(=O)[C@H](CO)c3ccccc3)C[C@@H]1[C@H]1O[C@@H]21
Identifiers
PDB—
CAS-ID51-34-3
RxCUI—
ChEMBL IDCHEMBL569713
ChEBI ID16794
PubChem CID153311
DrugBankDB00747
UNII ID—
Target
Agency Approved
CHRM1
CHRM1
CHRM3
CHRM3
Organism
Homo sapiens
Gene name
CHRM1
Gene synonyms
NCBI Gene ID
1128
Protein name
muscarinic acetylcholine receptor M1
Protein synonyms
acetylcholine receptor, muscarinic 1
Uniprot ID
Q96RH1
Mouse ortholog
Chrm1 (12669)
muscarinic acetylcholine receptor M1 (Q8BJN3)
Alternate
CHRM2
CHRM2
CHRM4
CHRM4
CHRM5
CHRM5
Organism
Homo sapiens
Gene name
CHRM2
Gene synonyms
NCBI Gene ID
1129
Protein name
muscarinic acetylcholine receptor M2
Protein synonyms
7TM receptor, acetylcholine receptor, muscarinic 2, muscarinic M2 receptor
Uniprot ID
Q9P1X9
Mouse ortholog
Chrm2 (243764)
muscarinic acetylcholine receptor M2 (Q9ERZ4)
Variants
No data
Financial
Revenue by drug
$
€
£
₣
No data
Estimated US medical usage
Scopolamine
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Number of purchases
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Refill frequency
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Price per prescription (USD)
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Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 25,153 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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5,303 adverse events reported
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