Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Prostatic neoplasms | D011471 | — | C61 | 1 | 1 | 1 | — | — | 2 |
Castration-resistant prostatic neoplasms | D064129 | — | — | 1 | 1 | 1 | — | — | 2 |
Severe acute respiratory syndrome | D045169 | EFO_0000694 | J12.81 | — | 1 | 1 | — | — | 2 |
Covid-19 | D000086382 | — | — | — | — | 1 | — | — | 1 |
Infections | D007239 | EFO_0000544 | — | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Breast neoplasms | D001943 | EFO_0003869 | C50 | — | 2 | — | — | — | 2 |
Respiratory distress syndrome | D012128 | EFO_1000637 | J80 | — | 1 | — | — | — | 1 |
Acute lung injury | D055371 | EFO_0004610 | — | — | 1 | — | — | — | 1 |
Newborn respiratory distress syndrome | D012127 | — | P22 | — | 1 | — | — | — | 1 |
Syndrome | D013577 | — | — | — | 1 | — | — | — | 1 |
Triple negative breast neoplasms | D064726 | — | — | — | 1 | — | — | — | 1 |
Drug common name | Sabizabulin |
INN | sabizabulin |
Description | Sabizabulin is a chemical compound from the group of indole and imidazole derivatives that was first reported in 2012 by Dalton, Li, and Miller. It is being studied as a mitotic inhibitor and chemotherapeutic agent in castration-resistant metastatic prostate cancer and in SARS-CoV-2 (COVID-19) infections.
|
Classification | Small molecule |
Drug class | antineoplastics (mitotic inhibitors; tubulin binders) |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | COc1cc(C(=O)c2c[nH]c(-c3c[nH]c4ccccc34)n2)cc(OC)c1OC |
PDB | — |
CAS-ID | 1332881-26-1 |
RxCUI | — |
ChEMBL ID | CHEMBL2163631 |
ChEBI ID | — |
PubChem CID | 53379371 |
DrugBank | — |
UNII ID | 37L1JX37J5 (ChemIDplus, GSRS) |