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Drug ReportsSabizabulin
Sabizabulin
Sabizabulin is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
6 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Prostatic neoplasmsD011471C611112
Castration-resistant prostatic neoplasmsD0641291112
Severe acute respiratory syndromeD045169EFO_0000694J12.81112
Covid-19D00008638211
InfectionsD007239EFO_000054411
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Breast neoplasmsD001943EFO_0003869C5022
Respiratory distress syndromeD012128EFO_1000637J8011
Acute lung injuryD055371EFO_000461011
Newborn respiratory distress syndromeD012127P2211
SyndromeD01357711
Triple negative breast neoplasmsD06472611
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameSabizabulin
INNsabizabulin
Description
Sabizabulin is a chemical compound from the group of indole and imidazole derivatives that was first reported in 2012 by Dalton, Li, and Miller. It is being studied as a mitotic inhibitor and chemotherapeutic agent in castration-resistant metastatic prostate cancer and in SARS-CoV-2 (COVID-19) infections.
Classification
Small molecule
Drug classantineoplastics (mitotic inhibitors; tubulin binders)
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Structure (InChI/SMILES or Protein Sequence)
COc1cc(C(=O)c2c[nH]c(-c3c[nH]c4ccccc34)n2)cc(OC)c1OC
Identifiers
PDB
CAS-ID1332881-26-1
RxCUI
ChEMBL IDCHEMBL2163631
ChEBI ID
PubChem CID53379371
DrugBank
UNII ID37L1JX37J5 (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 49 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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