SUNOBINOP
Sunobinop is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Events Timeline
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Commercial
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Clinical
Clinical Trials
6 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Alcoholism | D000437 | EFO_0003829 | F10.1 | — | 2 | — | — | — | 2 |
| Alcohol drinking | D000428 | EFO_0004329 | — | — | 2 | — | — | — | 2 |
| Postoperative pain | D010149 | — | G89.18 | — | 1 | — | — | — | 1 |
| Sleep initiation and maintenance disorders | D007319 | — | F51.01 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Syndrome | D013577 | — | — | 2 | — | — | — | — | 2 |
| Overactive urinary bladder | D053201 | EFO_1000781 | N32.81 | 1 | — | — | — | — | 1 |
| Interstitial cystitis | D018856 | EFO_1000869 | N30.1 | 1 | — | — | — | — | 1 |
| Cystitis | D003556 | EFO_1000025 | N30 | 1 | — | — | — | — | 1 |
| Somatoform disorders | D013001 | — | F45 | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | SUNOBINOP |
| INN | sunobinop |
| Description | Sunobinop (developmental code name IMB-115) is a nociceptin receptor partial agonist and opioid receptor pan-antagonist. As of March 2022, it is under investigation for the treatment of insomnia, fibromyalgia, and overactive bladder.
|
| Classification | Small molecule |
| Drug class | Nociceptin receptor agonist |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | O=C(O)c1nc2ccccc2n(C2C[C@@H]3CCC[C@@H](C2)N3C2C[C@H]3CCC[C@H](C2)C3)c1=O |
Identifiers
| PDB | — |
| CAS-ID | 1126793-40-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4650344 |
| ChEBI ID | — |
| PubChem CID | 155801560 |
| DrugBank | — |
| UNII ID | I1X86U5474 (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
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Additional graphs summarizing 5 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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