

Indication  | MeSH  | Ontology  | ICD-10  | Ph 1  | Ph 2  | Ph 3  | Ph 4  | Other  | Total  | 
|---|---|---|---|---|---|---|---|---|---|
| Rheumatoid arthritis | D001172 | EFO_0000685 | M06.9 | — | 1 | — | — | — | 1 | 
| Arthritis | D001168 | EFO_0005856 | M05-M14 | — | 1 | — | — | — | 1 | 
Indication  | MeSH  | Ontology  | ICD-10  | Ph 1  | Ph 2  | Ph 3  | Ph 4  | Other  | Total  | 
|---|---|---|---|---|---|---|---|---|---|
| Lymphoma | D008223 | — | C85.9 | 3 | — | — | — | — | 3 | 
| B-cell chronic lymphocytic leukemia | D015451 | — | C91.1 | 3 | — | — | — | — | 3 | 
| B-cell lymphoma | D016393 | — | — | 2 | — | — | — | — | 2 | 
| Leukemia | D007938 | — | C95 | 2 | — | — | — | — | 2 | 
| Lymphoid leukemia | D007945 | — | C91 | 2 | — | — | — | — | 2 | 
| Healthy volunteers/patients | — | — | — | 2 | — | — | — | — | 2 | 
| Large b-cell lymphoma diffuse | D016403 | — | C83.3 | 1 | — | — | — | — | 1 | 
| B-cell leukemia | D015448 | — | — | 1 | — | — | — | — | 1 | 
| Non-hodgkin lymphoma | D008228 | — | C85.9 | 1 | — | — | — | — | 1 | 
| Waldenstrom macroglobulinemia | D008258 | — | C88.0 | 1 | — | — | — | — | 1 | 
| Drug common name | SPEBRUTINIB | 
| INN | spebrutinib | 
| Description | Spebrutinib besylate is a small molecule pharmaceutical. It is currently being investigated in clinical studies.  | 
| Classification | Small molecule  | 
| Drug class | tyrosine kinase inhibitors: tyrosine kinase inhibitors Bruton's (Btk) inhibitors | 
| Image (chem structure or protein) | ![]()  | 
| Structure (InChI/SMILES or Protein Sequence) | C=CC(=O)Nc1cccc(Nc2nc(Nc3ccc(OCCOC)cc3)ncc2F)c1.O=S(=O)(O)c1ccccc1  | 
| PDB | — | 
| CAS-ID | 1360053-81-1 | 
| RxCUI | — | 
| ChEMBL ID | CHEMBL3301600 | 
| ChEBI ID | — | 
| PubChem CID | 74892828 | 
| DrugBank | — | 
| UNII ID | DRU6NG543J (ChemIDplus, GSRS) | 
