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Drug ReportsSOLCITINIB
SOLCITINIB
Solcitinib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against tyrosine-protein kinase JAK1. In addition, it is known to target non-receptor tyrosine-protein kinase TYK2, tyrosine-protein kinase JAK2, and tyrosine-protein kinase JAK3.
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Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
7 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients22
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameSOLCITINIB
INNsolcitinib
Description
Solcitinib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against tyrosine-protein kinase JAK1. In addition, it is known to target non-receptor tyrosine-protein kinase TYK2, tyrosine-protein kinase JAK2, and tyrosine-protein kinase JAK3.
Classification
Small molecule
Drug classtyrosine kinase inhibitors: tyrosine kinase inhibitors; janus kinase inhibitors
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Structure (InChI/SMILES or Protein Sequence)
CC1(C)CN(C(=O)c2ccc(-c3cccc4nc(NC(=O)C5CC5)nn34)cc2)C1
Identifiers
PDB
CAS-ID
RxCUI
ChEMBL IDCHEMBL3301606
ChEBI ID
PubChem CID
DrugBank
UNII ID3V7GQ1260K (ChemIDplus, GSRS)
Target
Agency Approved
JAK1
JAK1
Organism
Homo sapiens
Gene name
JAK1
Gene synonyms
JAK1A, JAK1B
NCBI Gene ID
Protein name
tyrosine-protein kinase JAK1
Protein synonyms
JAK-1, Janus kinase 1
Uniprot ID
Mouse ortholog
Jak1 (16451)
tyrosine-protein kinase JAK1 (P52332)
Alternate
TYK2
TYK2
JAK2
JAK2
JAK3
JAK3
Organism
Homo sapiens
Gene name
TYK2
Gene synonyms
NCBI Gene ID
Protein name
non-receptor tyrosine-protein kinase TYK2
Protein synonyms
Uniprot ID
Mouse ortholog
Tyk2 (54721)
non-receptor tyrosine-protein kinase TYK2 (Q9R117)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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