Therapeutic Area | MeSH |
---|---|
cardiovascular diseases | D002318 |
nutritional and metabolic diseases | D009750 |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
CRESTOR | AstraZeneca | N-021366 RX | 2003-08-12 | 4 products, RLD, RS |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
ROSZET | Althera Pharmaceutical | N-213072 DISCN | 2021-03-23 | 4 products, RLD |
Brand Name | Status | Last Update |
---|---|---|
crestor | New Drug Application | 2024-07-31 |
ezallor sprinkle | New Drug Application | 2025-03-11 |
rosuvastatin | ANDA | 2025-04-07 |
rosuvastatin calcium | ANDA | 2025-04-02 |
rosuvastatin rosuvastatin calcium | ANDA | 2025-01-17 |
Expiration | Code | ||
---|---|---|---|
ROSUVASTATIN CALCIUM, CRESTOR, IPR | |||
2023-05-27 | ODE-118 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 2 | — | — | — | — | 2 |
Drug common name | Rosuvastatin |
INN | rosuvastatin |
Description | Rosuvastatin is a dihydroxy monocarboxylic acid that is (6E)-7-{4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl} hept-6-enoic acid carrying two hydroxy substituents at positions 3 and 5 (the 3R,5S-diastereomer). It has a role as an antilipemic drug, an anti-inflammatory agent, a CETP inhibitor, a cardioprotective agent, a xenobiotic and an environmental contaminant. It is a member of pyrimidines, a sulfonamide, a dihydroxy monocarboxylic acid, a statin (synthetic) and a member of monofluorobenzenes. It is functionally related to a hept-6-enoic acid. It is a conjugate acid of a rosuvastatin(1-). |
Classification | Small molecule |
Drug class | enzyme inhibitors: antihyperlipidemics (HMG-CoA inhibitors) |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | CC(C)c1nc(N(C)S(C)(=O)=O)nc(-c2ccc(F)cc2)c1/C=C/[C@@H](O)C[C@@H](O)CC(=O)O |
PDB | — |
CAS-ID | 287714-41-4 |
RxCUI | — |
ChEMBL ID | CHEMBL1496 |
ChEBI ID | 38545 |
PubChem CID | 446157 |
DrugBank | DB01098 |
UNII ID | 413KH5ZJ73 (ChemIDplus, GSRS) |