Brand Name | Status | Last Update |
---|---|---|
nplate | Biologic Licensing Application | 2022-02-17 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
thrombocytopenic purpura idiopathic | EFO_0007160 | D016553 | D69.3 |
Expiration | Code | ||
---|---|---|---|
romiplostim, Nplate, Amgen Inc. | |||
2028-01-28 | Orphan excl. |
Code | Description |
---|---|
J2796 | Injection, romiplostim, 10 micrograms |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Thrombocytopenia | D013921 | HP_0001873 | D69.6 | 5 | 26 | 16 | 5 | 12 | 60 |
Thrombocytopenic purpura idiopathic | D016553 | EFO_0007160 | D69.3 | 3 | 12 | 15 | 4 | 10 | 40 |
Thrombocytopenic purpura | D011696 | — | — | 2 | 7 | 11 | 2 | 5 | 24 |
Purpura | D011693 | HP_0000979 | D69.2 | 2 | 7 | 11 | 2 | 5 | 24 |
Aplastic anemia | D000741 | HP_0001915 | D61.9 | 1 | 6 | 3 | 3 | 1 | 11 |
Anemia | D000740 | HP_0001903 | D64.9 | — | 6 | 3 | 3 | 1 | 10 |
Liver diseases | D008107 | HP_0002910 | K70-K77 | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Neoplasms | D009369 | — | C80 | 3 | 4 | 1 | — | — | 6 |
Ovarian neoplasms | D010051 | EFO_0003893 | C56 | — | 1 | 1 | — | — | 2 |
Non-small-cell lung carcinoma | D002289 | — | — | — | 1 | 1 | — | — | 2 |
Lung neoplasms | D008175 | HP_0100526 | C34.90 | — | 1 | 1 | — | — | 2 |
Ovarian epithelial carcinoma | D000077216 | — | — | — | 1 | 1 | — | — | 2 |
Colorectal neoplasms | D015179 | — | — | — | — | 1 | — | — | 1 |
Vaccine immunogenicity | D000071497 | — | — | — | — | 1 | — | — | 1 |
Healthy volunteers/patients | — | — | — | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Syndrome | D013577 | — | — | — | 6 | — | — | 2 | 8 |
Myelodysplastic syndromes | D009190 | — | D46 | 1 | 5 | — | — | 1 | 7 |
Preleukemia | D011289 | — | — | 1 | 5 | — | — | 1 | 7 |
Lymphoma | D008223 | — | C85.9 | 2 | 5 | — | — | — | 5 |
Non-hodgkin lymphoma | D008228 | — | C85.9 | 2 | 4 | — | — | — | 4 |
Wiskott-aldrich syndrome | D014923 | EFO_0003903 | D82.0 | — | 1 | — | — | 1 | 2 |
Pancytopenia | D010198 | HP_0001876 | D61.81 | 1 | 1 | — | — | — | 2 |
Cytopenia | D000095542 | — | — | 1 | 1 | — | — | — | 2 |
Multiple myeloma | D009101 | — | C90.0 | — | 2 | — | — | — | 2 |
Hodgkin disease | D006689 | — | C81 | 1 | 2 | — | — | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Bone marrow failure disorders | D000080983 | — | — | 1 | — | — | — | — | 1 |
Hematologic neoplasms | D019337 | — | — | 1 | — | — | — | — | 1 |
Pharmacokinetics | D010599 | — | — | 1 | — | — | — | — | 1 |
Therapeutic equivalency | D013810 | — | — | 1 | — | — | — | — | 1 |
Pharmacological phenomena | D000069437 | — | — | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Splenectomy | D013156 | — | — | — | — | — | — | 1 | 1 |
Congenital abnormalities | D000013 | EFO_0003915 | Q89.9 | — | — | — | — | 1 | 1 |
Spontaneous abortion | D000022 | EFO_1001255 | O00.1 | — | — | — | — | 1 | 1 |
Birth weight | D001724 | EFO_0004344 | — | — | — | — | — | 1 | 1 |
Drug common name | Romiplostim |
INN | romiplostim |
Description | L-methionyl[human immunogloblin heavy constant gamma 1-(227 C-terminal residues)-peptide (Fc fragment)] fusion protein with 41 amino acids peptide, (7-7':10,10')-bisdisulfide dimer |
Classification | Protein |
Drug class | colony-stimulating factors |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | — |
PDB | — |
CAS-ID | — |
RxCUI | — |
ChEMBL ID | CHEMBL1201832 |
ChEBI ID | — |
PubChem CID | — |
DrugBank | DB05332 |
UNII ID | GN5XU2DXKV (ChemIDplus, GSRS) |