Therapeutic Area | MeSH |
---|---|
infections | D007239 |
respiratory tract diseases | D012140 |
Brand Name | Status | Last Update |
---|---|---|
priftin | New Drug Application | 2025-05-21 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
pulmonary tuberculosis | EFO_1000049 | D014397 | A15 |
latent tuberculosis | — | D055985 | Z22.7 |
mycobacterium infections | — | D009164 | A31.9 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Tuberculosis | D014376 | EFO_0000774 | A15-A19 | 14 | 18 | 26 | 8 | 10 | 66 |
Latent tuberculosis | D055985 | — | Z22.7 | 6 | 4 | 12 | 4 | 4 | 26 |
Infections | D007239 | EFO_0000544 | — | 2 | 2 | 6 | 1 | 1 | 11 |
Hiv | D006678 | — | O98.7 | 2 | 2 | 1 | 1 | 1 | 6 |
Chronic kidney failure | D007676 | EFO_0003884 | N18.6 | — | — | — | 2 | — | 2 |
Kidney diseases | D007674 | EFO_0003086 | N08 | — | — | — | 2 | — | 2 |
Hiv seropositivity | D006679 | — | — | 1 | 1 | — | 1 | — | 2 |
Patient compliance | D010349 | — | — | — | — | — | 1 | — | 1 |
Renal insufficiency | D051437 | — | N19 | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Pulmonary tuberculosis | D014397 | EFO_1000049 | A15 | 1 | 6 | 6 | — | — | 11 |
Hiv infections | D015658 | EFO_0000764 | B20 | 2 | 3 | 3 | — | 3 | 10 |
Communicable diseases | D003141 | — | — | 1 | 2 | 3 | — | 1 | 6 |
Mycobacterium infections | D009164 | — | A31.9 | 1 | 1 | 1 | — | — | 3 |
Acquired immunodeficiency syndrome | D000163 | EFO_0000765 | B20 | 1 | — | 1 | — | 1 | 3 |
Mycobacterium tuberculosis | D009169 | NCBITaxon_1773 | — | 1 | — | 1 | — | — | 2 |
Silicosis | D012829 | EFO_0007485 | J62 | — | — | 1 | — | 1 | 2 |
Latent infection | D000085343 | — | — | — | 1 | 1 | — | 1 | 2 |
Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | — | — | 1 | — | — | 1 |
Infertility | D007246 | EFO_0000545 | — | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Mycobacterium avium-intracellulare infection | D015270 | EFO_0007386 | — | — | 1 | — | — | — | 1 |
Bacteremia | D016470 | EFO_0003033 | R78.81 | — | 1 | — | — | — | 1 |
Respiratory tract infections | D012141 | — | J06.9 | 1 | 1 | — | — | — | 1 |
Pregnancy | D011247 | EFO_0002950 | Z33.1 | 1 | 1 | — | — | — | 1 |
Spinal tuberculosis | D014399 | — | A18.01 | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 3 | — | — | — | — | 3 |
Osteomyelitis | D010019 | EFO_0003102 | M86 | 1 | — | — | — | — | 1 |
Drug interactions | D004347 | — | — | 1 | — | — | — | — | 1 |
Breast feeding | D001942 | — | — | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Opioid-related disorders | D009293 | EFO_0005611 | F11 | — | — | — | — | 1 | 1 |
Hepatitis | D006505 | — | K75.9 | — | — | — | — | 1 | 1 |
Addictive behavior | D016739 | EFO_0004347 | — | — | — | — | — | 1 | 1 |
Silicotuberculosis | D012830 | — | J65 | — | — | — | — | 1 | 1 |
Only child | D009863 | — | — | — | — | — | — | 1 | 1 |
Adolescent development | D041923 | — | — | — | — | — | — | 1 | 1 |
Drug common name | Rifapentine |
INN | rifapentine |
Description | Rifapentine, sold under the brand name Priftin, is an antibiotic used in the treatment of tuberculosis. In active tuberculosis it is used together with other antituberculosis medications. In latent tuberculosis it is typically used with isoniazid. It is taken by mouth.
|
Classification | Small molecule |
Drug class | antibiotics (rifamycin derivatives) |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | CO[C@H]1/C=C/O[C@@]2(C)Oc3c(C)c(O)c4c(O)c(c(/C=N/N5CCN(C6CCCC6)CC5)c(O)c4c3C2=O)NC(=O)/C(C)=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C |
PDB | — |
CAS-ID | 61379-65-5 |
RxCUI | — |
ChEMBL ID | CHEMBL1660 |
ChEBI ID | 45304 |
PubChem CID | 6323497 |
DrugBank | DB01201 |
UNII ID | XJM390A33U (ChemIDplus, GSRS) |