Tradename | Company | Number | Date | Products |
---|---|---|---|---|
RIMACTANE | Oxford Pharmaceuticals | N-050429 RX | 1982-01-01 | 1 products |
RIFADIN | Sanofi | N-050627 RX | 1989-05-25 | 1 products, RLD, RS |
Brand Name | Status | Last Update |
---|---|---|
mycobutin | New Drug Application | 2024-12-24 |
priftin | New Drug Application | 2025-05-21 |
rifabutin | NDA authorized generic | 2025-09-30 |
rifadin | 2007-07-16 | |
rifadin iv | New Drug Application | 2025-05-14 |
rifadin iv novaplus | New Drug Application | 2025-05-14 |
rifadin rifadin iv | New Drug Application | 2021-12-01 |
rifadin rifadin iv novaplus | New Drug Application | 2017-05-04 |
rifampin | ANDA | 2025-09-19 |
talicia | New Drug Application | 2024-05-01 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Tuberculosis | D014376 | EFO_0000774 | A15-A19 | 35 | 81 | 50 | 29 | 62 | 239 |
Healthy volunteers/patients | — | — | — | 118 | 1 | 1 | 1 | 5 | 125 |
Pulmonary tuberculosis | D014397 | EFO_1000049 | A15 | 6 | 52 | 30 | 6 | 17 | 100 |
Hiv infections | D015658 | EFO_0000764 | B20 | 9 | 21 | 16 | 12 | 12 | 64 |
Infections | D007239 | EFO_0000544 | — | 3 | 6 | 10 | 4 | 12 | 34 |
Multidrug-resistant tuberculosis | D018088 | EFO_0007381 | — | — | 7 | 9 | 2 | 11 | 27 |
Communicable diseases | D003141 | — | — | — | 3 | 6 | 3 | 10 | 22 |
Drug interactions | D004347 | — | — | 18 | 1 | — | 3 | 1 | 22 |
Latent tuberculosis | D055985 | — | Z22.7 | 3 | 4 | 8 | 4 | 6 | 22 |
Acquired immunodeficiency syndrome | D000163 | EFO_0000765 | B20 | 2 | 4 | 6 | 4 | 7 | 21 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Meningeal tuberculosis | D014390 | — | A17.0 | 1 | 9 | 3 | — | 1 | 12 |
Coinfection | D060085 | — | — | — | 3 | 2 | — | 2 | 7 |
Alzheimer disease | D000544 | EFO_0000249 | F03 | 1 | — | 3 | — | 1 | 5 |
Aids-related opportunistic infections | D017088 | — | — | — | — | 1 | — | 4 | 5 |
Meningitis | D008581 | EFO_0000584 | G03 | — | 2 | 1 | — | 1 | 4 |
Buruli ulcer | D054312 | EFO_1001281 | A31.1 | — | 3 | 2 | — | 1 | 4 |
Pneumonia | D011014 | EFO_0003106 | J18 | 1 | 2 | 1 | — | — | 3 |
Sepsis | D018805 | EFO_0001420 | A41.9 | 1 | — | 1 | — | 1 | 3 |
Uveitis | D014605 | EFO_1001231 | H20.9 | — | 1 | 1 | — | 1 | 3 |
Immunologic deficiency syndromes | D007153 | — | D84.9 | — | — | 2 | — | 1 | 3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Neoplasms | D009369 | — | C80 | 33 | 1 | — | — | — | 34 |
Myeloid leukemia acute | D015470 | — | C92.0 | 7 | 7 | — | — | — | 11 |
Lymphoma | D008223 | — | C85.9 | 8 | 1 | — | — | — | 9 |
Myelodysplastic syndromes | D009190 | — | D46 | 3 | 5 | — | — | — | 7 |
Melanoma | D008545 | — | — | 4 | 3 | — | — | — | 6 |
Pharmacokinetics | D010599 | — | — | 4 | 1 | — | — | — | 5 |
Recurrence | D012008 | — | — | 4 | 2 | — | — | — | 5 |
Sarcoidosis | D012507 | EFO_0000690 | D80-D89 | 2 | 2 | — | — | 1 | 4 |
Myeloproliferative disorders | D009196 | — | D47.1 | 3 | 1 | — | — | — | 4 |
Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | C91.0 | 1 | 3 | — | — | — | 4 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Non-hodgkin lymphoma | D008228 | — | C85.9 | 8 | — | — | — | — | 8 |
Non-small-cell lung carcinoma | D002289 | — | — | 6 | — | — | — | — | 6 |
Neoplasm metastasis | D009362 | EFO_0009708 | — | 3 | — | — | — | — | 3 |
Primary myelofibrosis | D055728 | — | D47.4 | 2 | — | — | — | — | 2 |
Biological availability | D001682 | — | — | 2 | — | — | — | — | 2 |
Thrombosis | D013927 | — | — | 2 | — | — | — | — | 2 |
Bacterial infections | D001424 | — | A49 | 1 | — | — | — | 1 | 2 |
Respiratory syncytial virus infections | D018357 | EFO_1001413 | — | 2 | — | — | — | — | 2 |
Parkinson disease | D010300 | EFO_0002508 | G20 | 2 | — | — | — | — | 2 |
Rhinoscleroma | D012226 | EFO_0007470 | — | 2 | — | — | — | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Critical illness | D016638 | — | — | — | — | — | — | 2 | 2 |
Body weight | D001835 | EFO_0004338 | — | — | — | — | — | 2 | 2 |
Metabolic syndrome | D024821 | EFO_0000195 | E88.810 | — | — | — | — | 2 | 2 |
Bone diseases | D001847 | — | M89.9 | — | — | — | — | 1 | 1 |
Infectious bone diseases | D001850 | — | — | — | — | — | — | 1 | 1 |
Acinetobacter infections | D000151 | EFO_1000792 | — | — | — | — | — | 1 | 1 |
Scrub typhus | D012612 | EFO_0007480 | A75.3 | — | — | — | — | 1 | 1 |
Epidemic louse-borne typhus | D014438 | EFO_0007182 | A75 | — | — | — | — | 1 | 1 |
Birth weight | D001724 | EFO_0004344 | — | — | — | — | — | 1 | 1 |
Granuloma | D006099 | — | — | — | — | — | — | 1 | 1 |
Drug common name | Rifampin |
INN | rifampicin |
Description | Rifampicin, also known as rifampin, is an ansamycin antibiotic used to treat several types of bacterial infections, including tuberculosis (TB), Mycobacterium avium complex, leprosy, and Legionnaires' disease. It is almost always used together with other antibiotics with two notable exceptions: when given as a "preferred treatment that is strongly recommended" for latent TB infection; and when used as post-exposure prophylaxis to prevent Haemophilus influenzae type b and meningococcal disease in people who have been exposed to those bacteria. Before treating a person for a long period of time, measurements of liver enzymes and blood counts are recommended. Rifampicin may be given either by mouth or intravenously.
|
Classification | Small molecule |
Drug class | tricyclic compounds; antibiotics (rifamycin derivatives) |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | CO[C@H]1/C=C/O[C@@]2(C)Oc3c(C)c(O)c4c(O)c(c(/C=N/N5CCN(C)CC5)c(O)c4c3C2=O)NC(=O)/C(C)=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C |
PDB | — |
CAS-ID | 13292-46-1 |
RxCUI | — |
ChEMBL ID | CHEMBL374478 |
ChEBI ID | 28077 |
PubChem CID | 5381226 |
DrugBank | DB01045 |
UNII ID | VJT6J7R4TR (ChemIDplus, GSRS) |