Tradename | Company | Number | Date | Products |
---|---|---|---|---|
VIRAZOLE | Bausch Health Companies | N-018859 RX | 1985-12-31 | 1 products, RLD, RS |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Chronic hepatitis c | D019698 | EFO_0004220 | B18.2 | 23 | 146 | 143 | 97 | 118 | 511 |
Hepatitis c | D006526 | — | B19.2 | 28 | 117 | 98 | 62 | 71 | 350 |
Hiv infections | D015658 | EFO_0000764 | B20 | 11 | 23 | 12 | 15 | 11 | 68 |
Hepacivirus | D016174 | — | — | 4 | 22 | 17 | 7 | 9 | 53 |
Chronic hepatitis b | D019694 | EFO_0004239 | B18.1 | 4 | 23 | 23 | 4 | 3 | 50 |
Hepatitis b | D006509 | — | — | 2 | 13 | 15 | 2 | 7 | 36 |
Liver cirrhosis | D008103 | EFO_0001422 | K74.0 | — | 7 | 19 | 3 | 7 | 33 |
Hiv | D006678 | — | O98.7 | 2 | 4 | 4 | 5 | 4 | 18 |
Hepatitis | D006505 | HP_0012115 | K75.9 | 1 | 6 | 6 | 1 | 1 | 13 |
Liver neoplasms | D008113 | EFO_1001513 | C22.0 | — | 2 | 3 | 4 | 2 | 11 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Covid-19 | D000086382 | — | U07.1 | 2 | 5 | 2 | — | 5 | 13 |
Lassa fever | D007835 | EFO_0007338 | A96.2 | — | 4 | 1 | — | 3 | 7 |
Chronic hepatitis | D006521 | — | K73.9 | 1 | 1 | 2 | — | 2 | 6 |
Fibrosis | D005355 | — | — | — | 1 | 3 | — | 2 | 6 |
Infections | D007239 | EFO_0000544 | — | — | 1 | 3 | — | 1 | 5 |
Pneumonia | D011014 | EFO_0003106 | — | — | 2 | 1 | — | 2 | 4 |
Experimental liver cirrhosis | D008106 | — | — | — | 2 | 1 | — | — | 2 |
Respiratory syncytial virus infections | D018357 | EFO_1001413 | — | — | 1 | 1 | — | — | 2 |
Menopause | D008593 | EFO_0003922 | N95 | — | — | 1 | — | — | 1 |
Self efficacy | D020377 | — | — | — | 1 | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 7 | 1 | — | — | 1 | 8 |
Myeloid leukemia acute | D015470 | — | C92.0 | 3 | 5 | — | — | — | 5 |
Major depressive disorder | D003865 | EFO_0003761 | F22 | — | 1 | — | — | 2 | 3 |
Human influenza | D007251 | EFO_0007328 | J11.1 | 1 | 3 | — | — | — | 3 |
Heart failure | D006333 | HP_0001635 | I50 | 1 | 1 | — | — | 1 | 2 |
Viral hepatitis human | D006525 | EFO_0004196 | — | 1 | 1 | — | — | — | 2 |
Viral hemorrhagic fevers | D006482 | — | A99 | — | 1 | — | — | 1 | 2 |
Hemorrhagic fever with renal syndrome | D006480 | EFO_0007299 | A98.5 | — | 2 | — | — | — | 2 |
Respiratory tract infections | D012141 | — | J06.9 | — | 1 | — | — | — | 1 |
Bronchiolitis obliterans | D001989 | EFO_0007183 | — | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Head and neck neoplasms | D006258 | — | — | 1 | — | — | — | 1 | 2 |
Hepatic insufficiency | D048550 | — | — | 1 | — | — | — | — | 1 |
Squamous cell neoplasms | D018307 | — | — | 1 | — | — | — | — | 1 |
Follicular lymphoma | D008224 | — | C82 | 1 | — | — | — | — | 1 |
Mantle-cell lymphoma | D020522 | — | C83.1 | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Mental disorders | D001523 | EFO_0000677 | F91.9 | — | — | — | — | 2 | 2 |
Pregnancy complications | D011248 | — | — | — | — | — | — | 2 | 2 |
Hemorrhage | D006470 | MP_0001914 | R58 | — | — | — | — | 1 | 1 |
Hypertension | D006973 | EFO_0000537 | I10 | — | — | — | — | 1 | 1 |
Menorrhagia | D008595 | EFO_0003945 | N92.0 | — | — | — | — | 1 | 1 |
Pain | D010146 | EFO_0003843 | R52 | — | — | — | — | 1 | 1 |
Down syndrome | D004314 | EFO_0001064 | Q90 | — | — | — | — | 1 | 1 |
Mucocutaneous lymph node syndrome | D009080 | EFO_0004246 | M30.3 | — | — | — | — | 1 | 1 |
Hyperaldosteronism | D006929 | HP_0011736 | E26 | — | — | — | — | 1 | 1 |
Pulmonary arterial hypertension | D000081029 | — | — | — | — | — | — | 1 | 1 |
Drug common name | Ribavirin |
INN | ribavirin |
Description | Ribavirin is a white powder and exists in two polymorphic forms. Ribavirin is a 1-ribosyltriazole that is the 1-ribofuranosyl derivative of 1,2,4-triazole-3-carboxamide. A synthetic guanosine analogue, it is an inhibitor of HCV polymerase and possesses a broad spectrum of activity against DNA and RNA viruses. It has a role as an antimetabolite, an antiviral agent, an antiinfective agent and an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor. It is a 1-ribosyltriazole, an aromatic amide and a monocarboxylic acid amide. Ribavirin is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses. Ribavirin is incorporated into viral RNA, thereby inhibiting viral RNA synthesis, inducing viral genome mutations, and inhibiting normal viral replication. |
Classification | Small molecule |
Drug class | antivirals |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | NC(=O)c1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)n1 |
PDB | — |
CAS-ID | 36791-04-5 |
RxCUI | — |
ChEMBL ID | CHEMBL1643 |
ChEBI ID | 63580 |
PubChem CID | 37542 |
DrugBank | DB00811 |
UNII ID | 49717AWG6K (ChemIDplus, GSRS) |