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Drug ReportsRetinol
Retinol
Berocca Pn, Infuvite, M.v.c. 9+, M.v.i, M.v.i. Lyophilized, Mvc, Vitamin A, Vitaped (retinol) is a small molecule pharmaceutical. Retinol was first approved as Aquasol a on 1982-01-01. It is known to target nuclear receptor subfamily 2 group C member 2.
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EMA approval date
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name
Status
Last Update
5% retinolC2002632024-10-16
acne relief retinol treatment and moisturizerOTC monograph final2022-02-10
acne wipeout clinical acne systemOTC monograph final2020-10-15
advanced retinol moisturizerC2002632024-10-20
advanced retinol rejuvenating eye creamC2002632024-11-07
anyi beauty retinol brightening anti aging face creamC2002632024-04-29
aoao retinol anti-aging box setC2002632025-01-08
aoao retinol anti-aging eye creamC2002632024-11-06
aoao retinol anti-aging milkC2002632024-11-07
aoao retinol anti-aging neck creamC2002632024-11-07
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Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
A: Alimentary tract and metabolism drugs
A11: Vitamins
A11C: Vitamin a and d, incl. combinations of the two
A11CA: Vitamin a, plain
A11CA01: Retinol (vit a)
D: Dermatologicals
D10: Anti-acne preparations
D10A: Anti-acne preparations for topical use
D10AD: Retinoids for topical use in acne
D10AD02: Retinol
R: Respiratory system drugs
R01: Nasal preparations
R01A: Decongestants and other nasal preparations for topical use
R01AX: Other nasal preparations in atc
R01AX02: Retinol
S: Sensory organ drugs
S01: Ophthalmologicals
S01X: Other ophthalmologicals in atc
S01XA: Other ophthalmologicals in atc
S01XA02: Retinol
HCPCS
No data
Clinical
Clinical Trials
3102 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Chronic renal insufficiencyD051436N1821529
Secondary hyperparathyroidismD006962EFO_10011731517
Kidney diseasesD007674EFO_0003086N0821316
HyperparathyroidismD006961EFO_0008506E21.3134
Neoplasm metastasisD009362EFO_000970833
Diabetic nephropathiesD003928EFO_0000401112
Renal dialysisD006435EFO_0010690Z99.2112
Vitamin d deficiencyD014808EFO_0003762E5522
Cardiovascular diseasesD002318EFO_0000319I98112
DialysisD00395611
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Breast feedingD00194211
LactationD00777411
Gastric bypassD015390EFO_000524411
Indications Phases 2
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Kidney transplantationD01603011
Pulmonary fibrosisD011658J84.1011
Healthy dietD00007200111
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameRetinol
INNretinol
Description
All-trans-retinol is a retinol in which all four exocyclic double bonds have E- (trans-) geometry. It has a role as a human metabolite, a mouse metabolite and a plant metabolite. It is a retinol and a vitamin A.
Classification
Small molecule
Drug classretinol derivatives
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CC1=C(/C=C/C(C)=C/C=C/C(C)=C/CO)C(C)(C)CCC1
Identifiers
PDB
CAS-ID11103-57-4
RxCUI
ChEMBL IDCHEMBL986
ChEBI ID17336
PubChem CID445354
DrugBankDB00162
UNII IDG2SH0XKK91 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
NR2C2
NR2C2
Organism
Homo sapiens
Gene name
NR2C2
Gene synonyms
TAK1, TR4
NCBI Gene ID
Protein name
nuclear receptor subfamily 2 group C member 2
Protein synonyms
Nuclear hormone receptor TR4, Orphan nuclear receptor TAK1, Orphan nuclear receptor TR4, orphan receptor TR4, testicular nuclear receptor 4, Testicular receptor 4
Uniprot ID
Mouse ortholog
Nr2c2 (22026)
nuclear receptor subfamily 2 group C member 2 (P55093)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 44,259 documents
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Safety
Black-box Warning
Black-box warning for: Prenatal plus multivitamin plus dha minicaps
Adverse Events
Top Adverse Reactions
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68,882 adverse events reported
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