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Drug ReportsRetinol
Retinol
Berocca Pn, Infuvite, M.v.c. 9+, M.v.i, M.v.i. Lyophilized, Mvc, Vitamin A, Vitaped (retinol) is a small molecule pharmaceutical. Retinol was first approved as Vitamin a solubilized on 1982-01-01. It is known to target nuclear receptor subfamily 2 group C member 2.
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Clinical
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Target
Variants
Financial
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Events Timeline
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name
Status
Last Update
5% retinolC2002632024-10-16
acne relief retinol treatment and moisturizerOTC monograph final2022-02-10
acne wipeout clinical acne systemOTC monograph final2020-10-15
advanced retinol moisturizerC2002632024-10-20
advanced retinol rejuvenating eye creamC2002632024-11-07
anyi beauty retinol brightening anti aging face creamC2002632024-04-29
aquasol aNew Drug Application2020-08-14
beautyturess retinol creamC2002632024-10-09
blemish dots - retinol (10 patches)C2002632024-07-14
brotege good boy protection spf 15 and retinol daily moisturizerC2002632024-08-09
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Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
A: Alimentary tract and metabolism drugs
A11: Vitamins
A11C: Vitamin a and d, incl. combinations of the two
A11CA: Vitamin a, plain
A11CA01: Retinol (vit a)
D: Dermatologicals
D10: Anti-acne preparations
D10A: Anti-acne preparations for topical use
D10AD: Retinoids for topical use in acne
D10AD02: Retinol
R: Respiratory system drugs
R01: Nasal preparations
R01A: Decongestants and other nasal preparations for topical use
R01AX: Other nasal preparations in atc
R01AX02: Retinol
S: Sensory organ drugs
S01: Ophthalmologicals
S01X: Other ophthalmologicals in atc
S01XA: Other ophthalmologicals in atc
S01XA02: Retinol
HCPCS
No data
Clinical
Clinical Trials
6426 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Acne vulgarisD000152EFO_0003894L70213
Type 2 diabetes mellitusD003924EFO_0001360E1111
Human influenzaD007251EFO_0007328J11.111
Common coldD003139EFO_0007214J0011
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
PsoriasisD011565EFO_0000676L40224
OsteoporosisD010024EFO_0003882M81.0123
InfectionsD007239EFO_0000544213
Respiratory tract infectionsD012141J06.922
Postmenopausal osteoporosisD015663EFO_000385411
Neoplasm metastasisD009362EFO_000970811
Bone fracturesD050723EFO_0003931T14.811
MalariaD008288EFO_0001068B5411
Yellow feverD015004A9511
RubellaD012409B0611
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Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
DyslipidemiasD0501711113
Rheumatoid arthritisD001172EFO_0000685M06.9122
ArthritisD001168EFO_0005856M05-M14122
Atrial fibrillationD001281EFO_0000275I48.011
Pancreatic neoplasmsD010190EFO_0003860C2511
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
HyperalgesiaD00693011
ToxoplasmosisD014123EFO_0007517B5811
FlushingD005483R23.211
Healthy volunteers/patients11
Bacterial infectionsD001424A4911
DengueD003715A9011
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Congenital abnormalitiesD000013EFO_0003915Q89.911
Depressive disorderD003866EFO_1002014F32.A11
Growth and developmentD04878811
Sickle cell anemiaD000755EFO_0000697D5711
Yin deficiencyD01671011
Insulin resistanceD007333EFO_0002614E88.81911
Abdominal obesityD05612811
Lipid metabolismD05035611
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameRetinol
INNretinol
Description
All-trans-retinol is a retinol in which all four exocyclic double bonds have E- (trans-) geometry. It has a role as a human metabolite, a mouse metabolite and a plant metabolite. It is a retinol and a vitamin A.
Classification
Small molecule
Drug classretinol derivatives
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CC1=C(/C=C/C(C)=C/C=C/C(C)=C/CO)C(C)(C)CCC1
Identifiers
PDB
CAS-ID11103-57-4
RxCUI
ChEMBL IDCHEMBL986
ChEBI ID17336
PubChem CID445354
DrugBankDB00162
UNII IDG2SH0XKK91 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
NR2C2
NR2C2
Organism
Homo sapiens
Gene name
NR2C2
Gene synonyms
TAK1, TR4
NCBI Gene ID
Protein name
nuclear receptor subfamily 2 group C member 2
Protein synonyms
Nuclear hormone receptor TR4, Orphan nuclear receptor TAK1, Orphan nuclear receptor TR4, orphan receptor TR4, testicular nuclear receptor 4, Testicular receptor 4
Uniprot ID
Mouse ortholog
Nr2c2 (22026)
nuclear receptor subfamily 2 group C member 2 (P55093)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 7,004 documents
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Safety
Black-box Warning
Black-box warning for: Prenatal plus multivitamin plus dha minicaps
Adverse Events
Top Adverse Reactions
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1,781 adverse events reported
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