Rescinnamine
Cinnasil, Moderil (rescinnamine) is a small molecule pharmaceutical. Rescinnamine was first approved as Moderil on 1982-01-01. It is used to treat hypertension in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| cardiovascular diseases | D002318 |
Trade Name
FDA
EMA
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Labels
FDA
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Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| hypertension | EFO_0000537 | D006973 | I10 |
Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
C: Cardiovascular system drugs
— C02: Antihypertensives
— C02A: Antiadrenergic agents, centrally acting
— C02AA: Rauwolfia alkaloids, centrally acting antiadrenergic
— C02AA01: Rescinnamine
— C02L: Antihypertensives and diuretics in combination
— C02LA: Rauwolfia alkaloids and diuretics in combination
— C02LA02: Rescinnamine and diuretics
— C02LA52: Rescinnamine and diuretics, combinations with other drugs
HCPCS
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Clinical
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Drug
General
| Drug common name | Rescinnamine |
| INN | rescinnamine |
| Description | Rescinnamine is a methyl ester, an organic heteropentacyclic compound and an indole alkaloid. It has a role as an antihypertensive agent. It derives from a hydride of a yohimban. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | COC(=O)[C@H]1[C@H]2C[C@@H]3c4[nH]c5cc(OC)ccc5c4CCN3C[C@H]2C[C@@H](OC(=O)/C=C/c2cc(OC)c(OC)c(OC)c2)[C@@H]1OC |
Identifiers
| PDB | — |
| CAS-ID | 24815-24-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1668 |
| ChEBI ID | 28572 |
| PubChem CID | 5280954 |
| DrugBank | DB01180 |
| UNII ID | Q6W1F7DJ2D (ChemIDplus, GSRS) |
Target
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Safety
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0 adverse events reported
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