Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Carcinoma | D002277 | — | C80.0 | 2 | 5 | 1 | — | — | 8 |
Squamous cell carcinoma | D002294 | — | — | — | 2 | 1 | — | — | 3 |
Squamous cell carcinoma of head and neck | D000077195 | — | — | — | 1 | 1 | — | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Multiple myeloma | D009101 | — | C90.0 | 6 | 1 | — | — | — | 6 |
Plasma cell neoplasms | D054219 | — | — | 6 | 1 | — | — | — | 6 |
Breast neoplasms | D001943 | EFO_0003869 | C50 | 2 | 3 | — | — | — | 5 |
Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 1 | 3 | — | — | — | 4 |
Recurrence | D012008 | — | — | 2 | 2 | — | — | — | 4 |
Lung neoplasms | D008175 | HP_0100526 | C34.90 | — | 3 | — | — | — | 3 |
Adenocarcinoma | D000230 | — | — | 1 | 2 | — | — | — | 3 |
Melanoma | D008545 | — | — | 1 | 3 | — | — | — | 3 |
Colorectal neoplasms | D015179 | — | — | 1 | 1 | — | — | — | 2 |
Non-small-cell lung carcinoma | D002289 | — | — | — | 2 | — | — | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Neoplasms | D009369 | — | C80 | 2 | — | — | — | — | 2 |
Glioma | D005910 | EFO_0000520 | — | 2 | — | — | — | — | 2 |
Anemia | D000740 | HP_0001903 | D64.9 | 1 | — | — | — | — | 1 |
Brain neoplasms | D001932 | EFO_0003833 | C71 | 1 | — | — | — | — | 1 |
Glioblastoma | D005909 | EFO_0000515 | — | 1 | — | — | — | — | 1 |
Medulloblastoma | D008527 | — | — | 1 | — | — | — | — | 1 |
Rhabdoid tumor | D018335 | — | — | 1 | — | — | — | — | 1 |
Astrocytoma | D001254 | EFO_0000271 | — | 1 | — | — | — | — | 1 |
Diffuse intrinsic pontine glioma | D000080443 | — | — | 1 | — | — | — | — | 1 |
Oligodendroglioma | D009837 | EFO_0000631 | — | 1 | — | — | — | — | 1 |
Drug common name | Pelareorep |
INN | — |
Description | Pelareorep (previously known under the trademark Reolysin) is a proprietary isolate of the unmodified human reovirus being developed as a systemically administered immuno-oncological viral agent for the treatment of solid tumors and hematological malignancies. Pelareorep is an oncolytic virus, which means that it preferentially lyses cancer cells. Pelareorep also promotes an inflamed tumor phenotype through innate and adaptive immune responses. Preliminary clinical trials indicate that it may have anti-cancer effects across a variety of cancer types (including breast, colorectal and pancreatic, as well as multiple myeloma) when administered alone and in combination with other cancer therapies.
|
Classification | Unknown |
Drug class | — |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | — |
PDB | — |
CAS-ID | — |
RxCUI | — |
ChEMBL ID | CHEMBL3545069 |
ChEBI ID | — |
PubChem CID | — |
DrugBank | — |
UNII ID | — |