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Drug ReportsReboxetine
Reboxetine
Reboxetine is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against sodium-dependent noradrenaline transporter.
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Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
behavior and behavior mechanismsD001520
mental disordersD001523
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
N: Nervous system drugs
— N06: Psychoanaleptics
— N06A: Antidepressants
— N06AX: Other antidepressants in atc
— N06AX18: Reboxetine
HCPCS
No data
Clinical
Clinical Trials
38 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
DepressionD003863—F33.9—1———1
Major depressive disorderD003865EFO_0003761F22—1———1
Depressive disorderD003866EFO_1002014F32.A—1———1
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameReboxetine
INNreboxetine
Description
Reboxetine is an aromatic ether.
Classification
Small molecule
Drug classantidepressants (fluoxetine type)
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CCOc1ccccc1OC(c1ccccc1)C1CNCCO1
Identifiers
PDB—
CAS-ID105017-38-7
RxCUI—
ChEMBL IDCHEMBL14370
ChEBI ID—
PubChem CID127151
DrugBankDB00234
UNII ID947S0YZ36I (ChemIDplus, GSRS)
Target
Agency Approved
SLC6A2
SLC6A2
Organism
Homo sapiens
Gene name
SLC6A2
Gene synonyms
NAT1, NET1, SLC6A5
NCBI Gene ID
Protein name
sodium-dependent noradrenaline transporter
Protein synonyms
NET, neurotransmitter transporter, Norepinephrine transporter, solute carrier family 6 (neurotransmitter transporter), member 2, solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2, Solute carrier family 6 member 2, solute carrier family 6 member 5
Uniprot ID
Mouse ortholog
Slc6a2 (20538)
sodium-dependent noradrenaline transporter (Q6QU62)
Alternate
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 3,544 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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436 adverse events reported
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