Ramosetron
Ramosetron is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
66 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Vomiting | D014839 | — | R11.1 | — | 3 | 4 | 9 | 17 | 33 |
| Nausea | D009325 | — | R11.0 | — | 3 | 4 | 6 | 13 | 26 |
| Postoperative nausea and vomiting | D020250 | EFO_0004888 | — | — | 2 | 1 | 9 | 10 | 22 |
| Syndrome | D013577 | — | — | 1 | 2 | 3 | 2 | 1 | 9 |
| Irritable bowel syndrome | D043183 | EFO_0000555 | K58 | — | 2 | 3 | 2 | 1 | 8 |
| Diarrhea | D003967 | — | R19.7 | — | 2 | 2 | 2 | 1 | 7 |
| Neoplasms | D009369 | — | C80 | — | 1 | 1 | 1 | 1 | 4 |
| Digestive signs and symptoms | D012817 | — | — | — | — | — | 1 | — | 1 |
| Ambulatory surgical procedures | D000556 | — | — | — | — | — | 1 | — | 1 |
| Bone fractures | D050723 | EFO_0003931 | T14.8 | — | — | — | 1 | — | 1 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | — | 1 | 1 | — | — | 2 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | — | — | 1 | — | — | 1 |
| Leiomyoma | D007889 | — | D25 | — | — | 1 | — | — | 1 |
| Adenomyosis | D062788 | EFO_1001757 | N80.0 | — | — | 1 | — | — | 1 |
| Myofibroma | D047708 | — | — | — | — | 1 | — | — | 1 |
| Fecal incontinence | D005242 | — | R15 | — | 1 | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Postoperative pain | D010149 | — | G89.18 | — | 1 | — | — | 3 | 4 |
| Ovarian epithelial carcinoma | D000077216 | — | — | — | 1 | — | — | — | 1 |
| Lung neoplasms | D008175 | — | C34.90 | — | 1 | — | — | — | 1 |
| Hematologic neoplasms | D019337 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 2 | — | — | — | — | 2 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hypotension | D007022 | EFO_0005251 | I95 | — | — | — | — | 2 | 2 |
| Electroacupuncture | D015671 | — | — | — | — | — | — | 1 | 1 |
| Colorectal neoplasms | D015179 | — | — | — | — | — | — | 1 | 1 |
| Rotator cuff injuries | D000070636 | — | M75.1 | — | — | — | — | 1 | 1 |
| Shivering | D012768 | — | — | — | — | — | — | 1 | 1 |
| Laparoscopic cholecystectomy | D017081 | — | — | — | — | — | — | 1 | 1 |
| Hysteroscopy | D015907 | — | — | — | — | — | — | 1 | 1 |
| Prostatic neoplasms | D011471 | — | C61 | — | — | — | — | 1 | 1 |
| Coronary artery bypass | D001026 | EFO_0003776 | — | — | — | — | — | 1 | 1 |
| Colonic neoplasms | D003110 | — | C18 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Ramosetron |
| INN | ramosetron |
| Description | Ramosetron is a member of indoles. |
| Classification | Small molecule |
| Drug class | serotonin 5-HT3 receptor antagonists |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Cn1cc(C(=O)[C@@H]2CCc3[nH]cnc3C2)c2ccccc21 |
Identifiers
| PDB | — |
| CAS-ID | 132036-88-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1643895 |
| ChEBI ID | — |
| PubChem CID | 108000 |
| DrugBank | — |
| UNII ID | 7ZRO0SC54Y (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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45 adverse events reported
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