Raclopride
Raclopride is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target D(3) dopamine receptor, D(2) dopamine receptor, D(4) dopamine receptor, and 5-hydroxytryptamine receptor 1A.
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Clinical Trials
35 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Psychotic disorders | D011618 | — | F20.81 | 1 | — | — | 1 | 3 | 5 |
| Depression | D003863 | — | F33.9 | 1 | — | — | 1 | 2 | 4 |
| Mental disorders | D001523 | EFO_0000677 | F91.9 | 1 | — | — | 1 | 1 | 3 |
| Cocaine-related disorders | D019970 | — | F14 | 1 | — | — | 1 | 1 | 3 |
| Feeding and eating disorders | D001068 | — | F50 | — | — | — | 1 | 1 | 2 |
| Smoking | D012907 | EFO_0004318 | — | — | — | — | 1 | — | 1 |
| Substance-related disorders | D019966 | EFO_0003890 | F13 | — | — | — | 1 | — | 1 |
| Anhedonia | D059445 | — | R45.84 | — | — | — | 1 | — | 1 |
Indications Phases 3
No data
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Traumatic brain injuries | D000070642 | — | S06 | 1 | 2 | — | — | — | 3 |
| Brain injuries | D001930 | — | S06.9 | 1 | 2 | — | — | — | 3 |
| Parkinson disease | D010300 | EFO_0002508 | G20 | — | 1 | — | — | 1 | 2 |
| Attention deficit disorder with hyperactivity | D001289 | EFO_0003888 | F90 | — | 1 | — | — | — | 1 |
| Cognition disorders | D003072 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Schizophrenia | D012559 | EFO_0000692 | F20 | 1 | — | — | — | 5 | 6 |
| Healthy volunteers/patients | — | — | — | 3 | — | — | — | 1 | 4 |
| Obesity | D009765 | EFO_0001073 | E66.9 | 1 | — | — | — | 1 | 2 |
| Overweight | D050177 | — | E66.3 | 1 | — | — | — | — | 1 |
| Huntington disease | D006816 | Orphanet_399 | G10 | 1 | — | — | — | — | 1 |
| Opioid-related disorders | D009293 | EFO_0005611 | F11 | 1 | — | — | — | — | 1 |
| Wounds and injuries | D014947 | — | T14.8 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Major depressive disorder | D003865 | EFO_0003761 | F22 | — | — | — | — | 2 | 2 |
| Depressive disorder | D003866 | EFO_1002014 | F32.A | — | — | — | — | 2 | 2 |
| Delusions | D003702 | — | — | — | — | — | — | 1 | 1 |
| Paranoid schizophrenia | D012563 | — | F20.0 | — | — | — | — | 1 | 1 |
| Treatment-resistant depressive disorder | D061218 | — | — | — | — | — | — | 1 | 1 |
| Tobacco use disorder | D014029 | — | F17 | — | — | — | — | 1 | 1 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | — | — | — | 1 | 1 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | — | — | — | — | 1 | 1 |
| Anorexia | D000855 | — | R63.0 | — | — | — | — | 1 | 1 |
| Anorexia nervosa | D000856 | EFO_0004215 | F50.0 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Raclopride |
| INN | raclopride |
| Description | 3,5-dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide is a member of salicylamides. |
| Classification | Small molecule |
| Drug class | sulpride derivatives and analogs |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC |
Identifiers
| PDB | — |
| CAS-ID | 104953-11-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL8809 |
| ChEBI ID | — |
| PubChem CID | 3033769 |
| DrugBank | — |
| UNII ID | 430K3SOZ7G (ChemIDplus, GSRS) |
Target
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Safety
Black-box Warning
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Adverse Events
0 adverse events reported
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