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Drug ReportsROPSACITINIB
ROPSACITINIB
Ropsacitinib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target tyrosine-protein kinase JAK1, tyrosine-protein kinase JAK2, and non-receptor tyrosine-protein kinase TYK2.
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Commercial
No data
Clinical
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Drug
General
Drug common nameROPSACITINIB
INNropsacitinib
Description
Ropsacitinib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target tyrosine-protein kinase JAK1, tyrosine-protein kinase JAK2, and non-receptor tyrosine-protein kinase TYK2.
Classification
Small molecule
Drug classtyrosine kinase inhibitors: tyrosine kinase inhibitors; janus kinase inhibitors
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
Cn1cc(-c2cn3nccc3c(-c3cnn([C@]4(CC#N)C[C@@H](C#N)C4)c3)n2)cn1
Identifiers
PDB
CAS-ID2127109-84-4
RxCUI
ChEMBL IDCHEMBL4459585
ChEBI ID
PubChem CID130339268
DrugBankDB18709
UNII IDHY5SOV7O0Q (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
JAK1
JAK1
JAK2
JAK2
TYK2
TYK2
Organism
Homo sapiens
Gene name
JAK1
Gene synonyms
JAK1A, JAK1B
NCBI Gene ID
Protein name
tyrosine-protein kinase JAK1
Protein synonyms
JAK-1, Janus kinase 1
Uniprot ID
Mouse ortholog
Jak1 (16451)
tyrosine-protein kinase JAK1 (P52332)
Variants
No data
Financial
No data
Trends
No data
Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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