RADALBUVIR
Radalbuvir is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
6 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hepatitis c | D006526 | — | B19.2 | 1 | 1 | — | — | 1 | 3 |
| Chronic hepatitis c | D019698 | EFO_0004220 | B18.2 | — | 2 | — | — | — | 2 |
| Hemophilia a | D006467 | EFO_0007267 | D66 | — | 1 | — | — | — | 1 |
| Chronic hepatitis b | D019694 | EFO_0004239 | B18.1 | — | 1 | — | — | — | 1 |
| Hepatitis | D006505 | — | K75.9 | — | 1 | — | — | — | 1 |
| Infections | D007239 | EFO_0000544 | — | — | 1 | — | — | — | 1 |
| Communicable diseases | D003141 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Fibrosis | D005355 | — | — | — | — | — | — | 1 | 1 |
| Hepatitis b | D006509 | — | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | RADALBUVIR |
| INN | radalbuvir |
| Description | Radalbuvir (INN, also known as GS-9669) is an experimental antiviral drug for the treatment of hepatitis C virus (HCV) infection developed by Gilead Sciences. Radalbuvir acts as an NS5B inhibitor. It is currently in clinical trials. It targets NS5B polymerase.
|
| Classification | Small molecule |
| Drug class | antivirals: RNA polymerase (NS5B) inhibitors |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC1=CC[C@H](C(=O)N(c2cc(C#CC(C)(C)C)sc2C(=O)O)[C@H]2CC[C@](O)(CO[C@H]3CCOC3)CC2)CC1 |
Identifiers
| PDB | — |
| CAS-ID | 1314795-11-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3121539 |
| ChEBI ID | — |
| PubChem CID | 53259022 |
| DrugBank | — |
| UNII ID | 273K4V0SPC (ChemIDplus, GSRS) |
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Trends
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Safety
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Adverse Events
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