Quilizumab
Quilizumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against Immunoglobulin heavy constant epsilon.
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Clinical
Clinical Trials
110 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Leukemia | D007938 | — | C95 | 17 | 29 | 20 | 1 | 3 | 65 |
| Myelodysplastic syndromes | D009190 | — | D46 | 1 | 6 | 8 | 1 | 1 | 15 |
| Preleukemia | D011289 | — | — | 1 | 5 | 8 | 1 | 1 | 14 |
| Syndrome | D013577 | — | — | — | 5 | 8 | 1 | 1 | 13 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | 1 | 2 | 3 | — | 6 |
| Lymphoma | D008223 | — | C85.9 | — | 4 | — | 1 | 1 | 6 |
| Diabetes mellitus | D003920 | HP_0000819 | E08-E13 | — | 1 | 2 | 2 | — | 5 |
| Anemia | D000740 | HP_0001903 | D64.9 | — | 1 | 2 | 1 | — | 4 |
| Multiple myeloma | D009101 | — | C90.0 | — | 2 | — | 1 | 1 | 4 |
| Plasma cell neoplasms | D054219 | — | — | — | 2 | — | 1 | 1 | 4 |
Show 6 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Myeloid leukemia | D007951 | — | C92 | 6 | 18 | 12 | — | 1 | 36 |
| Myeloid leukemia acute | D015470 | — | C92.0 | 6 | 18 | 11 | — | 1 | 35 |
| Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | — | 3 | 2 | 1 | — | 1 | 6 |
| Lymphoid leukemia | D007945 | — | C91 | 2 | 1 | 1 | — | 1 | 5 |
| Neoplasms | D009369 | — | C80 | 1 | 2 | 2 | — | — | 5 |
| Myeloproliferative disorders | D009196 | — | D47.1 | — | 1 | 3 | — | 1 | 5 |
| Myelodysplastic-myeloproliferative diseases | D054437 | — | — | — | 1 | 3 | — | — | 4 |
| Refractory anemia with excess of blasts | D000754 | — | D46.2 | — | — | 3 | — | — | 3 |
| Neutropenia | D009503 | — | D70 | — | 1 | 2 | — | — | 3 |
| Kidney transplantation | D016030 | — | — | — | — | 1 | — | 1 | 2 |
Show 14 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 3 | 1 | — | — | 1 | 4 |
| Carcinoma | D002277 | — | C80.0 | 1 | 1 | — | — | — | 2 |
| Asthma | D001249 | EFO_0000270 | J45 | — | 2 | — | — | — | 2 |
| Lymphoproliferative disorders | D008232 | Orphanet_2442 | D47.9 | — | 1 | — | — | — | 1 |
| Chronic pain | D059350 | HP_0012532 | — | — | 1 | — | — | — | 1 |
| Myofascial pain syndromes | D009209 | EFO_1001054 | — | — | 1 | — | — | — | 1 |
| Fibromyalgia | D005356 | EFO_0005687 | M79.1 | — | 1 | — | — | — | 1 |
| Large b-cell lymphoma diffuse | D016403 | — | C83.3 | — | 1 | — | — | — | 1 |
| B-cell lymphoma | D016393 | — | — | — | 1 | — | — | — | 1 |
| Inflammation | D007249 | MP_0001845 | — | — | 1 | — | — | — | 1 |
Show 11 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Bcr-abl positive chronic myelogenous leukemia | D015464 | EFO_0000340 | — | 2 | — | — | — | — | 2 |
| Macular edema | D008269 | — | — | 1 | — | — | — | — | 1 |
| Retinal diseases | D012164 | HP_0000479 | H35.9 | 1 | — | — | — | — | 1 |
| Radiation injuries | D011832 | — | — | 1 | — | — | — | — | 1 |
| Blast crisis | D001752 | — | — | 1 | — | — | — | — | 1 |
| Drug-related side effects and adverse reactions | D064420 | — | T88.7 | 1 | — | — | — | — | 1 |
| Hepatocellular carcinoma | D006528 | — | C22.0 | 1 | — | — | — | — | 1 |
| Allergic rhinitis | D065631 | — | J30.9 | 1 | — | — | — | — | 1 |
| Rhinitis | D012220 | EFO_0008521 | J31 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Parkinson disease | D010300 | EFO_0002508 | G20 | — | — | — | — | 2 | 2 |
| Covid-19 | D000086382 | — | — | — | — | — | — | 2 | 2 |
| Rosacea | D012393 | — | L71 | — | — | — | — | 1 | 1 |
| Stroke | D020521 | EFO_0000712 | I63.9 | — | — | — | — | 1 | 1 |
| Primary myelofibrosis | D055728 | — | D47.4 | — | — | — | — | 1 | 1 |
| Precancerous conditions | D011230 | — | — | — | — | — | — | 1 | 1 |
| Vasculitis | D014657 | HP_0002633 | — | — | — | — | — | 1 | 1 |
| Granulomatosis with polyangiitis | D014890 | EFO_0005297 | M31.3 | — | — | — | — | 1 | 1 |
| Anti-neutrophil cytoplasmic antibody-associated vasculitis | D056648 | — | I77.82 | — | — | — | — | 1 | 1 |
| Microscopic polyangiitis | D055953 | EFO_1000784 | M31.7 | — | — | — | — | 1 | 1 |
Show 16 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Quilizumab |
| INN | quilizumab |
| Description | Quilizumab (humanized mab) |
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2109456 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 26F96HRJ3W (ChemIDplus, GSRS) |
Target
Agency Approved
IGHE
IGHE
Organism
Homo sapiens
Gene name
IGHE
Gene synonyms
NCBI Gene ID
—
Protein name
Immunoglobulin heavy constant epsilon
Protein synonyms
Ig epsilon chain C region, Ig epsilon chain C region ND
Uniprot ID
Mouse ortholog
—
—
Alternate
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 88 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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