Quilizumab
Quilizumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against Immunoglobulin heavy constant epsilon.
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Clinical
Clinical Trials
33 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Leukemia | D007938 | — | C95 | — | 4 | 1 | 1 | — | 6 |
| Myelodysplastic syndromes | D009190 | — | D46 | — | 3 | — | 1 | — | 4 |
| Multiple myeloma | D009101 | — | C90.0 | — | 2 | — | 1 | — | 3 |
| Lymphoma | D008223 | — | C85.9 | — | 2 | — | 1 | — | 3 |
| Plasma cell neoplasms | D054219 | — | — | — | 2 | — | 1 | — | 3 |
| Syndrome | D013577 | — | — | — | 1 | 1 | 1 | — | 3 |
| Preleukemia | D011289 | — | — | — | 1 | — | 1 | — | 2 |
| Plasmacytoma | D010954 | — | C90.3 | — | 1 | — | 1 | — | 2 |
| Graft vs host disease | D006086 | — | D89.81 | — | — | — | 1 | — | 1 |
| Anemia | D000740 | EFO_0004272 | D64.9 | — | — | — | 1 | — | 1 |
Show 2 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Myeloid leukemia acute | D015470 | — | C92.0 | — | 4 | 1 | — | — | 5 |
| Kidney transplantation | D016030 | — | — | — | — | 1 | — | 1 | 2 |
| Myeloid leukemia | D007951 | — | C92 | — | 1 | 1 | — | — | 2 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Congenital abnormalities | D000013 | EFO_0003915 | Q89.9 | — | 3 | — | — | — | 3 |
| Megakaryoblastic leukemia acute | D007947 | — | C94.2 | — | 3 | — | — | — | 3 |
| Monocytic leukemia acute | D007948 | — | — | — | 3 | — | — | — | 3 |
| Myelomonocytic leukemia acute | D015479 | — | C92.5 | — | 3 | — | — | — | 3 |
| Erythroblastic leukemia acute | D004915 | EFO_1001257 | C94.0 | — | 3 | — | — | — | 3 |
| Asthma | D001249 | EFO_0000270 | J45 | — | 2 | — | — | — | 2 |
| Neoplasms | D009369 | — | C80 | 1 | 1 | — | — | — | 2 |
| Recurrence | D012008 | — | — | — | 1 | — | — | — | 1 |
| Myeloproliferative disorders | D009196 | — | D47.1 | — | 1 | — | — | — | 1 |
| Non-hodgkin lymphoma | D008228 | — | C85.9 | — | 1 | — | — | — | 1 |
Show 34 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Macular edema | D008269 | — | — | 1 | — | — | — | — | 1 |
| Retinal diseases | D012164 | — | H35.9 | 1 | — | — | — | — | 1 |
| Radiation injuries | D011832 | — | T66 | 1 | — | — | — | — | 1 |
| Carcinoma | D002277 | — | C80.0 | 1 | — | — | — | — | 1 |
| Hepatocellular carcinoma | D006528 | — | C22.0 | 1 | — | — | — | — | 1 |
| Allergic rhinitis | D065631 | — | J30.9 | 1 | — | — | — | — | 1 |
| Rhinitis | D012220 | EFO_0008521 | J31 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Covid-19 | D000086382 | — | U07.1 | — | — | — | — | 2 | 2 |
| Vasculitis | D014657 | EFO_0006803 | M31 | — | — | — | — | 1 | 1 |
| Granulomatosis with polyangiitis | D014890 | EFO_0005297 | M31.3 | — | — | — | — | 1 | 1 |
| Anti-neutrophil cytoplasmic antibody-associated vasculitis | D056648 | — | I77.82 | — | — | — | — | 1 | 1 |
| Microscopic polyangiitis | D055953 | EFO_1000784 | M31.7 | — | — | — | — | 1 | 1 |
| Ulcerative colitis | D003093 | EFO_0000729 | K51 | — | — | — | — | 1 | 1 |
| Colitis | D003092 | EFO_0003872 | K52.9 | — | — | — | — | 1 | 1 |
| Ulcer | D014456 | MPATH_579 | — | — | — | — | — | 1 | 1 |
| Sars-cov-2 | D000086402 | — | — | — | — | — | — | 1 | 1 |
| Pelvic organ prolapse | D056887 | EFO_0004710 | — | — | — | — | — | 1 | 1 |
Show 8 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Quilizumab |
| INN | quilizumab |
| Description | Quilizumab (humanized mab) |
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2109456 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 26F96HRJ3W (ChemIDplus, GSRS) |
Target
Agency Approved
IGHE
IGHE
Organism
Homo sapiens
Gene name
IGHE
Gene synonyms
NCBI Gene ID
—
Protein name
Immunoglobulin heavy constant epsilon
Protein synonyms
Ig epsilon chain C region, Ig epsilon chain C region ND
Uniprot ID
Mouse ortholog
—
—
Alternate
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 97 documents
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Safety
Black-box Warning
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Adverse Events
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