Pyronaridine
Pyronaridine is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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New Drug Application (NDA)
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Clinical
Clinical Trials
40 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Malaria | D008288 | EFO_0001068 | B54 | 7 | 7 | 10 | 4 | 2 | 28 |
| Falciparum malaria | D016778 | EFO_0007444 | B50 | 1 | 8 | 4 | 2 | 1 | 14 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Covid-19 | D000086382 | — | U07.1 | — | 4 | 3 | — | — | 6 |
| Vivax malaria | D016780 | EFO_0007445 | B51 | — | — | 2 | — | 1 | 3 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Schistosomiasis haematobia | D012553 | EFO_0007530 | B65.0 | — | 1 | — | — | — | 1 |
| Schistosomiasis | D012552 | EFO_1001475 | B65 | — | 1 | — | — | — | 1 |
| Coinfection | D060085 | — | — | — | 1 | — | — | — | 1 |
| Leukemia | D007938 | — | C95 | — | 1 | — | — | — | 1 |
| Myeloid leukemia acute | D015470 | — | C92.0 | — | 1 | — | — | — | 1 |
| Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | C91.0 | — | 1 | — | — | — | 1 |
| Myeloid leukemia | D007951 | — | C92 | — | 1 | — | — | — | 1 |
| Lymphoid leukemia | D007945 | — | C91 | — | 1 | — | — | — | 1 |
| Asymptomatic infections | D058345 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 2 | — | — | — | — | 2 |
| Recurrence | D012008 | — | — | 1 | — | — | — | — | 1 |
| Parasitic diseases | D010272 | EFO_0001067 | B88 | 1 | — | — | — | — | 1 |
| Parasitemia | D018512 | — | — | 1 | — | — | — | — | 1 |
| Protozoan infections | D011528 | — | B50-B64 | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Pyronaridine |
| INN | pyronaridine |
| Description | Pyronaridine is an antimalarial drug. It was first made in 1970 and has been in clinical use in China since the 1980s.
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | COc1ccc2nc3cc(Cl)ccc3c(Nc3cc(CN4CCCC4)c(O)c(CN4CCCC4)c3)c2n1 |
Identifiers
| PDB | — |
| CAS-ID | 74847-35-1 |
| RxCUI | — |
| ChEMBL ID | CHEMBL35228 |
| ChEBI ID | — |
| PubChem CID | 5485198 |
| DrugBank | — |
| UNII ID | TD3P7Q3SG6 (ChemIDplus, GSRS) |
Target
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Safety
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Adverse Events
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