Pyrethrins
Rid Mousse (pyrethrins) is a small molecule pharmaceutical. Pyrethrins was first approved as Rid mousse on 2000-03-07. It is used to treat lice infestations and scabies in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| infections | D007239 |
| skin and connective tissue diseases | D017437 |
Trade Name
FDA
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Labels
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Agency Specific
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Patent Expiration
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ATC Codes
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HCPCS
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Clinical
Clinical Trials
20 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Insecticide resistance | D007305 | — | — | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Malaria | D008288 | EFO_0001068 | B54 | — | — | 3 | — | 12 | 15 |
| Vector borne diseases | D000079426 | — | — | — | — | 1 | — | 1 | 2 |
| Emergencies | D004630 | — | — | — | — | 1 | — | — | 1 |
| Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | — | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Lice infestations | D010373 | — | B85.2 | — | 1 | — | — | 1 | 2 |
| Pediculus | D010374 | — | — | — | 1 | — | — | 1 | 2 |
Indications Phases 1
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Anemia | D000740 | HP_0001903 | D64.9 | — | — | — | — | 3 | 3 |
| Metabolism | D008660 | GO_0008152 | — | — | — | — | — | 1 | 1 |
| Pharmacokinetics | D010599 | — | — | — | — | — | — | 1 | 1 |
| Tinea capitis | D014006 | — | B35.0 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Pyrethrins |
| INN | — |
| Description | The pyrethrins are a class of organic compounds normally derived from Chrysanthemum cinerariifolium that have potent insecticidal activity by targeting the nervous systems of insects. Pyrethrin naturally occurs in chrysanthemum flowers and is often considered an organic insecticide when it is not combined with piperonyl butoxide or other synthetic adjuvants. Their insecticidal and insect-repellent properties have been known and used for thousands of years.
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C=C/C=C\CC1=C(C)[C@@H](OC(=O)[C@@H]2[C@@H](/C=C(\C)C(=O)OC)C2(C)C)CC1=O.C=C/C=C\CC1=C(C)[C@@H](OC(=O)[C@@H]2[C@@H](C=C(C)C)C2(C)C)CC1=O |
Identifiers
| PDB | — |
| CAS-ID | 8003-34-7 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2096637 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | — |
Target
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Estimated US medical usage
Pyrethrins
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Piperonyl butoxide
Total medical expenditures per year (USD, in millions)
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Trends
PubMed Central
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Additional graphs summarizing 3,120 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
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169 adverse events reported
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