Procaterol
Procaterol is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against beta-2 adrenergic receptor.
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New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Clinical
Clinical Trials
54 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Asthma | D001249 | EFO_0000270 | J45 | 5 | 5 | 19 | 5 | 2 | 36 |
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | 2 | — | 2 | 2 | 3 | 9 |
| Lung diseases | D008171 | HP_0002088 | J98.4 | — | — | 2 | 3 | 2 | 7 |
| Obstructive lung diseases | D008173 | HP_0006536 | — | 1 | — | 2 | 2 | 2 | 7 |
| Respiratory aspiration | D053120 | EFO_1001839 | — | — | — | — | 1 | 2 | 3 |
| Cough | D003371 | HP_0012735 | R05 | — | — | — | 1 | 1 | 2 |
| Emergencies | D004630 | — | — | — | — | 1 | 1 | — | 2 |
| Cough-variant asthma | D000096823 | — | — | — | — | — | 1 | — | 1 |
| Nicotiana | D014026 | NCBITaxon_4097 | — | — | — | — | 1 | — | 1 |
| Anaphylaxis | D000707 | — | T88.6 | — | — | — | 1 | — | 1 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Allergic rhinitis | D065631 | — | J30.9 | — | — | 1 | — | — | 1 |
| Rhinitis | D012220 | EFO_0008521 | J31 | — | — | 1 | — | — | 1 |
| Allergic rhinitis seasonal | D006255 | EFO_0003956 | J30 | — | — | 1 | — | — | 1 |
| Heart failure | D006333 | HP_0001635 | I50 | — | — | 1 | — | — | 1 |
| Vascular diseases | D014652 | EFO_0004264 | I77 | — | — | 1 | — | — | 1 |
Indications Phases 2
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Dyskinesias | D020820 | HP_0002310 | G24 | 1 | — | — | — | — | 1 |
| Ciliary motility disorders | D002925 | EFO_0003900 | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | — | — | — | — | 2 | 2 |
| Fibrosis | D005355 | — | — | — | — | — | — | 1 | 1 |
| Cystic fibrosis | D003550 | EFO_0000390 | E84 | — | — | — | — | 1 | 1 |
| Alpha 1-antitrypsin deficiency | D019896 | — | E88.01 | — | — | — | — | 1 | 1 |
| Argininosuccinic aciduria | D056807 | — | — | — | — | — | — | 1 | 1 |
| Disease progression | D018450 | — | — | — | — | — | — | 1 | 1 |
| Status asthmaticus | D013224 | — | — | — | — | — | — | 1 | 1 |
| Chronic cough | D000096822 | — | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Procaterol |
| INN | procaterol |
| Description | Procaterol is an intermediate-acting β2 adrenoreceptor agonist used for the treatment of asthma. It has never been filed for FDA evaluation in the United States, where it is not marketed. The drug is readily oxidized in the presence of moisture and air, making it unsuitable for therapeutic use by inhalation. Pharmaceutical company Parke-Davis/Warner-Lambert researched a stabilizer to prevent oxidation, but an effective one was never developed.
|
| Classification | Small molecule |
| Drug class | bronchodilators (phenethylamine derivatives) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCC(NC(C)C)C(O)c1ccc(O)c2[nH]c(=O)ccc12 |
Identifiers
| PDB | — |
| CAS-ID | 72332-33-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL160519 |
| ChEBI ID | — |
| PubChem CID | 688561 |
| DrugBank | — |
| UNII ID | X7I3EMM5K0 (ChemIDplus, GSRS) |
Target
Agency Approved
ADRB2
ADRB2
Organism
Homo sapiens
Gene name
ADRB2
Gene synonyms
ADRB2R, B2AR
NCBI Gene ID
Protein name
beta-2 adrenergic receptor
Protein synonyms
adrenergic, beta-2-, receptor, surface, adrenoceptor beta 2 surface, Beta-2 adrenoceptor, Beta-2 adrenoreceptor, catecholamine receptor
Uniprot ID
Mouse ortholog
Adrb2 (11555)
beta-2 adrenergic receptor (Q8BH38)
Alternate
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Variants
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Financial
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Trends
PubMed Central
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Additional graphs summarizing 545 documents
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Safety
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Adverse Events
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130 adverse events reported
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