Citanest, Fortacin(prilocaine)
/ Prilocaine, Citanest, Fortacin, Oraqix, Prilocaine (prilocaine) is a small molecule pharmaceutical. Prilocaine was first approved as Citanest forte on 1982-01-01. It is used to treat pain in the USA. It has been approved in Europe to treat physiological sexual dysfunction and premature ejaculation.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Trade Name
FDA
EMA
Prilocaine (discontinued: Citanest)
CombinationsCitanest, Lidocaine prilocaine, Oraqix, Prilocaine epinephrine (discontinued: Citanest, Emla, Lidocaine prilocaine)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Lidocaine
+
Prilocaine
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| ORAQIX | Dentsply Pharmaceutical | N-021451 RX | 2003-12-19 | 1 products, RLD, RS |
Show 2 discontinued
Prilocaine hydrochloride
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| CITANEST | AstraZeneca | N-014763 DISCN | 1982-01-01 | 3 products, RLD |
| CITANEST PLAIN | AstraZeneca | N-014763 DISCN | 1982-01-01 | 1 products, RLD |
| CITANEST PLAIN DENTAL | Dentsply Pharmaceutical | N-021382 DISCN | 1982-01-01 | 1 products, RLD |
Hide discontinued
Epinephrine bitartrate
+
Prilocaine hydrochloride
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| CITANEST FORTE DENTAL | Dentsply Pharmaceutical | N-021383 RX | 1982-01-01 | 1 products, RLD, RS |
Show 1 discontinued
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| agoneaze | unapproved drug other | 2018-04-18 |
| anodyne lpt | NDA authorized generic | 2017-03-17 |
| cadira compliant blood stat | unapproved drug other | 2018-11-01 |
| citanest forte dental | ANDA | 2024-02-29 |
| dermacinrx prikaan | NDA authorized generic | 2016-09-19 |
| dibucaine hcl 0.5% / lidocaine 15% / phenylephrine hcl 1% / prilocaine 5% | unapproved drug other | 2019-05-10 |
| inflammation reduction pack | ANDA | 2015-11-18 |
| lido bdk | unapproved drug other | 2018-11-01 |
| lido-prilo caine pack | NDA authorized generic | 2017-01-09 |
| lidocaine 15% / phenylephrine hcl 0.25% / prilocaine 5% | unapproved drug other | 2019-05-16 |
Show 17 more
Indications
FDA
EMA
Show 8 more
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
No data
Clinical
Clinical Trials
258 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pain | D010146 | EFO_0003843 | R52 | 2 | 4 | 6 | 6 | 11 | 28 |
| Postoperative pain | D010149 | — | G89.18 | 1 | — | — | 3 | 6 | 10 |
| Healthy volunteers/patients | — | — | — | 5 | — | — | 1 | 4 | 10 |
| Local anesthesia | D000772 | — | — | 1 | 2 | 2 | 2 | 4 | 10 |
| Spinal anesthesia | D000775 | — | — | 1 | — | — | 1 | 5 | 7 |
| Anesthesia | D000758 | — | — | 1 | — | — | 2 | 4 | 7 |
| Analgesia | D000698 | — | — | — | — | 1 | 1 | 4 | 6 |
| Brachial plexus block | D065527 | — | — | — | — | — | 3 | 2 | 5 |
| Contraception | D003267 | — | — | — | — | 3 | 2 | — | 5 |
| Actinic keratosis | D055623 | — | L57.0 | 3 | — | — | 1 | 1 | 5 |
Show 45 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Premature ejaculation | D061686 | — | F52.4 | 2 | 2 | 2 | — | 1 | 6 |
| Procedural pain | D000073818 | — | — | — | — | 1 | — | 4 | 5 |
| Premature birth | D047928 | EFO_0003917 | O60 | 1 | 2 | 2 | — | 1 | 5 |
| Hypotension | D007022 | EFO_0005251 | I95 | — | — | 1 | — | 1 | 2 |
| Infertility | D007246 | EFO_0000545 | — | — | — | 1 | — | 1 | 2 |
| Atrophy | D001284 | — | — | — | 1 | 1 | — | 1 | 2 |
| Systemic scleroderma | D012595 | EFO_0000717 | M34 | — | — | 1 | — | — | 1 |
| Neoplasm metastasis | D009362 | EFO_0009708 | — | — | — | 1 | — | — | 1 |
| Raynaud disease | D011928 | EFO_1001145 | I73.0 | — | — | 1 | — | — | 1 |
| Diffuse scleroderma | D045743 | EFO_0000404 | — | — | — | 1 | — | — | 1 |
Show 13 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neuralgia | D009437 | EFO_0009430 | — | — | 3 | — | — | 2 | 5 |
| Wounds and injuries | D014947 | — | T14.8 | — | 2 | — | — | 1 | 3 |
| Migraine disorders | D008881 | EFO_0003821 | G43 | 1 | 1 | — | — | 2 | 3 |
| Headache | D006261 | — | R51 | 1 | 1 | — | — | 2 | 3 |
| Neoplasms | D009369 | — | C80 | — | 1 | — | — | 2 | 3 |
| Back pain | D001416 | — | M54 | — | 1 | — | — | 1 | 2 |
| Cesarean section | D002585 | — | — | — | 1 | — | — | 1 | 2 |
| Cognitive dysfunction | D060825 | — | G31.84 | 1 | 1 | — | — | 1 | 2 |
| Carcinoma | D002277 | — | C80.0 | 1 | 1 | — | — | — | 2 |
| Ulcer | D014456 | MPATH_579 | — | — | 1 | — | — | 1 | 2 |
Show 21 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Skin diseases | D012871 | — | L00-L99 | 2 | — | — | — | — | 2 |
| Dental anesthesia | D000766 | — | — | 1 | — | — | — | 1 | 2 |
| Mouth diseases | D009059 | EFO_1001047 | K13 | 2 | — | — | — | — | 2 |
| Bowen's disease | D001913 | — | D00-D09 | 1 | — | — | — | — | 1 |
| Squamous cell carcinoma | D002294 | — | — | 1 | — | — | — | — | 1 |
| Compartment syndromes | D003161 | — | T79.A0 | 1 | — | — | — | — | 1 |
| Lentigo | D007911 | — | L81.4 | 1 | — | — | — | — | 1 |
| Topical administration | D000287 | — | — | 1 | — | — | — | — | 1 |
| Hidradenitis suppurativa | D017497 | — | L73.2 | 1 | — | — | — | — | 1 |
| Hidradenitis | D016575 | — | — | 1 | — | — | — | — | 1 |
Show 1 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Radiculopathy | D011843 | — | M54.1 | — | — | — | — | 5 | 5 |
| Intervertebral disc displacement | D007405 | EFO_1001800 | — | — | — | — | — | 5 | 5 |
| Pruritus | D011537 | — | L29 | — | — | — | — | 3 | 3 |
| Neck pain | D019547 | — | M54.2 | — | — | — | — | 3 | 3 |
| Stroke | D020521 | EFO_0000712 | I63.9 | — | — | — | — | 2 | 2 |
| Ambulatory surgical procedures | D000556 | — | — | — | — | — | — | 2 | 2 |
| Urinary incontinence | D014549 | — | R32 | — | — | — | — | 2 | 2 |
| Stress urinary incontinence | D014550 | — | — | — | — | — | — | 2 | 2 |
| Carotid stenosis | D016893 | — | — | — | — | — | — | 2 | 2 |
| Chronic pain | D059350 | — | — | — | — | — | — | 2 | 2 |
Show 87 more
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Prilocaine |
| INN | prilocaine |
| Description | Prilocaine is an amino acid amide in which N-propyl-DL-alanine and 2-methylaniline have combined to form the amide bond; used as a local anaesthetic. It has a role as a local anaesthetic and an anticonvulsant. It is an amino acid amide and a monocarboxylic acid amide. |
| Classification | Small molecule |
| Drug class | local anesthetics |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCCNC(C)C(=O)Nc1ccccc1C |
Identifiers
| PDB | — |
| CAS-ID | 721-50-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1194 |
| ChEBI ID | 8404 |
| PubChem CID | 4906 |
| DrugBank | DB00750 |
| UNII ID | 046O35D44R (ChemIDplus, GSRS) |
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
₣
No data
Estimated US medical usage
Prilocaine
+
Lidocaine
Total medical expenditures per year (USD, in millions)
Mock data
Subscribe for the real data
Subscribe for the real data
Number of persons purchased
Mock data
Subscribe for the real data
Subscribe for the real data
Number of purchases
Mock data
Subscribe for the real data
Subscribe for the real data
Refill frequency
Mock data
Subscribe for the real data
Subscribe for the real data
Price per prescription (USD)
Mock data
Subscribe for the real data
Subscribe for the real data
Prilocaine
Total medical expenditures per year (USD, in millions)
Mock data
Subscribe for the real data
Subscribe for the real data
Number of persons purchased
Mock data
Subscribe for the real data
Subscribe for the real data
Number of purchases
Mock data
Subscribe for the real data
Subscribe for the real data
Refill frequency
Mock data
Subscribe for the real data
Subscribe for the real data
Price per prescription (USD)
Mock data
Subscribe for the real data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 4,289 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
917 adverse events reported
View more details
© 2020-2025 Collaborative Drug Discovery Inc. (CDD) | Terms of Use