Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Post-traumatic stress disorders | D013313 | EFO_0001358 | F43.1 | 2 | 4 | 3 | 5 | 10 | 24 |
Alcoholism | D000437 | EFO_0003829 | F10.1 | 3 | 6 | 1 | 1 | 4 | 13 |
Hypertension | D006973 | EFO_0000537 | I10 | 2 | 1 | — | 1 | 3 | 7 |
Prostatic hyperplasia | D011470 | EFO_0000284 | N40 | — | — | — | 1 | 2 | 3 |
Fibrosis | D005355 | — | — | — | 1 | — | 1 | — | 2 |
Suicidal ideation | D059020 | EFO_0004320 | R45.851 | — | — | — | 1 | 1 | 2 |
Dreams | D004325 | — | — | — | — | — | 1 | 1 | 2 |
Portal hypertension | D006975 | EFO_0000666 | K76.6 | — | — | — | 2 | — | 2 |
Dementia | D003704 | EFO_0003862 | F03 | 1 | 1 | — | 1 | — | 2 |
Post-traumatic headache | D051298 | — | G44.3 | 1 | 1 | — | 1 | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Sleep wake disorders | D012893 | — | G47 | — | — | 1 | — | 3 | 4 |
Scorpion stings | D065008 | — | — | — | — | 1 | — | — | 1 |
Kidney calculi | D007669 | EFO_0004253 | N20 | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Alzheimer disease | D000544 | EFO_0000249 | F03 | — | 1 | — | — | 2 | 3 |
Combat disorders | D003130 | — | — | 1 | 1 | — | — | 2 | 3 |
Covid-19 | D000086382 | — | U07.1 | — | 1 | — | — | 1 | 2 |
Pheochromocytoma | D010673 | — | — | — | 1 | — | — | 1 | 2 |
Chronic hepatitis c | D019698 | EFO_0004220 | B18.2 | — | 1 | — | — | — | 1 |
Alcohol withdrawal delirium | D000430 | EFO_1000800 | — | 1 | 1 | — | — | — | 1 |
Problem behavior | D000066553 | — | — | — | 1 | — | — | — | 1 |
Traumatic stress disorders acute | D040701 | EFO_0005223 | F43.0 | — | 1 | — | — | — | 1 |
Neurogenic urinary bladder | D001750 | HP_0000011 | N31 | 1 | 1 | — | — | — | 1 |
Blood pressure | D001794 | EFO_0004325 | — | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Anxiety disorders | D001008 | EFO_0006788 | F41.1 | 1 | — | — | — | 1 | 2 |
Healthy volunteers/patients | — | — | — | 1 | — | — | — | 1 | 2 |
Cigarette smoking | D000073865 | — | — | 1 | — | — | — | — | 1 |
Cardiovascular diseases | D002318 | HP_0001626 | — | 1 | — | — | — | — | 1 |
Anxiety | D001007 | EFO_0005230 | F41.1 | 1 | — | — | — | — | 1 |
Heart failure | D006333 | HP_0001635 | I50 | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hip fractures | D006620 | EFO_0003964 | S72.00 | — | — | — | — | 2 | 2 |
Sleep initiation and maintenance disorders | D007319 | — | F51.01 | — | — | — | — | 2 | 2 |
Wounds and injuries | D014947 | — | T14.8 | — | — | — | — | 1 | 1 |
Pain | D010146 | EFO_0003843 | R52 | — | — | — | — | 1 | 1 |
Substance-related disorders | D019966 | EFO_0003890 | F13 | — | — | — | — | 1 | 1 |
Chronic disease | D002908 | — | — | — | — | — | — | 1 | 1 |
Brain injuries | D001930 | — | S06.9 | — | — | — | — | 1 | 1 |
Alcohol-related disorders | D019973 | — | F10 | — | — | — | — | 1 | 1 |
Depression | D003863 | — | F33.9 | — | — | — | — | 1 | 1 |
Cognitive dysfunction | D060825 | HP_0001268 | G31.84 | — | — | — | — | 1 | 1 |
Drug common name | Prazosin |
INN | prazosin |
Description | Prazosin is a member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively. It has a role as an antihypertensive agent, an alpha-adrenergic antagonist and an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor. It is a member of piperazines, a member of quinazolines, a member of furans, a monocarboxylic acid amide and an aromatic ether. |
Classification | Small molecule |
Drug class | antihypertensives (prazosin type) |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | COc1cc2nc(N3CCN(C(=O)c4ccco4)CC3)nc(N)c2cc1OC |
PDB | — |
CAS-ID | 19216-56-9 |
RxCUI | — |
ChEMBL ID | CHEMBL2 |
ChEBI ID | 8364 |
PubChem CID | 4893 |
DrugBank | DB00457 |
UNII ID | XM03YJ541D (ChemIDplus, GSRS) |