Therapeutic Area | MeSH |
---|---|
infections | D007239 |
stomatognathic diseases | D009057 |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
NOXAFIL | Merck & Co | N-205596 RX | 2014-03-13 | 1 products, RLD, RS |
NOXAFIL POWDERMIX KIT | Merck & Co | N-214770 RX | 2021-05-31 | 1 products, RLD, RS |
NOXAFIL | Merck & Co | N-022003 RX | 2006-09-15 | 1 products, RLD, RS |
Brand Name | Status | Last Update |
---|---|---|
noxafil | New Drug Application | 2024-10-25 |
posaconazole | ANDA | 2025-06-27 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
mycoses | — | D009181 | B35-B49 |
oral candidiasis | EFO_0007406 | D002180 | B37.0 |
Expiration | Code | ||
---|---|---|---|
POSACONAZOLE, NOXAFIL, MERCK SHARP DOHME | |||
2028-06-17 | ODE-355 | ||
2024-06-17 | I-881 | ||
2024-05-31 | NPP | ||
POSACONAZOLE, NOXAFIL POWDERMIX KIT, MSD MERCK CO | |||
2024-05-31 | NP |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Mycoses | D009181 | — | B35-B49 | 7 | 8 | 10 | 7 | 12 | 44 |
Invasive fungal infections | D000072742 | — | — | 4 | 3 | 7 | 5 | 7 | 26 |
Infections | D007239 | EFO_0000544 | — | 5 | 5 | 6 | 4 | 5 | 24 |
Myeloid leukemia acute | D015470 | — | C92.0 | 8 | 9 | 1 | 4 | 4 | 20 |
Leukemia | D007938 | — | C95 | 7 | 10 | — | 1 | 4 | 17 |
Myeloid leukemia | D007951 | — | C92 | 5 | 8 | 1 | 3 | 4 | 17 |
Communicable diseases | D003141 | — | — | 5 | 1 | 3 | 2 | 4 | 15 |
Aspergillosis | D001228 | EFO_0007157 | B44 | 1 | 2 | 4 | 2 | 4 | 12 |
Myelodysplastic syndromes | D009190 | — | D46 | 1 | 4 | 1 | 3 | 1 | 9 |
Invasive pulmonary aspergillosis | D055744 | — | B44.0 | 1 | 1 | 2 | 1 | 2 | 7 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Neoplasms | D009369 | — | C80 | 3 | 2 | 1 | — | — | 5 |
Invasive hydatidiform mole | D002820 | — | D39.2 | — | — | 1 | — | 3 | 4 |
Hiv infections | D015658 | EFO_0000764 | B20 | 1 | 1 | 1 | — | — | 3 |
Fibrosis | D005355 | — | — | — | 1 | 1 | — | 1 | 2 |
Cystic fibrosis | D003550 | EFO_0000390 | E84 | — | 1 | 1 | — | 1 | 2 |
Chronic granulomatous disease | D006105 | EFO_0000338 | D71 | — | 1 | 1 | — | — | 2 |
Oral candidiasis | D002180 | EFO_0007406 | B37.0 | — | 1 | 1 | — | — | 2 |
Candidemia | D058387 | EFO_1001282 | — | — | — | 1 | — | — | 1 |
Fungemia | D016469 | — | B49 | — | — | 1 | — | — | 1 |
Pneumocystis pneumonia | D011020 | EFO_0007448 | B59 | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Myeloproliferative disorders | D009196 | — | D47.1 | 1 | 2 | — | — | — | 2 |
Lymphoma | D008223 | — | C85.9 | 1 | 1 | — | — | — | 2 |
Onychomycosis | D014009 | — | B35.1 | — | 1 | — | — | 1 | 2 |
Chagas disease | D014355 | EFO_0008559 | B57 | — | 2 | — | — | — | 2 |
Mucormycosis | D009091 | EFO_0007380 | B46.5 | — | 1 | — | — | 1 | 2 |
Zygomycosis | D020096 | — | B46 | — | 1 | — | — | 1 | 2 |
Myelodysplastic-myeloproliferative diseases | D054437 | — | — | 1 | 1 | — | — | — | 1 |
Virus diseases | D014777 | — | B34 | — | 1 | — | — | — | 1 |
Respiratory syncytial virus infections | D018357 | EFO_1001413 | — | — | 1 | — | — | — | 1 |
Anemia | D000740 | EFO_0004272 | D64.9 | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 1 | — | — | — | 1 | 2 |
Multiple myeloma | D009101 | — | C90.0 | 1 | — | — | — | — | 1 |
Plasma cell neoplasms | D054219 | — | — | 1 | — | — | — | — | 1 |
Large b-cell lymphoma diffuse | D016403 | — | C83.3 | 1 | — | — | — | — | 1 |
Recurrence | D012008 | — | — | 1 | — | — | — | — | 1 |
Brain neoplasms | D001932 | EFO_0003833 | C71 | 1 | — | — | — | — | 1 |
Glioma | D005910 | EFO_0000520 | — | 1 | — | — | — | — | 1 |
Glioblastoma | D005909 | EFO_0000515 | — | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hematologic diseases | D006402 | EFO_0005803 | D75.9 | — | — | — | — | 3 | 3 |
Critical illness | D016638 | — | — | — | — | — | — | 2 | 2 |
Kidney diseases | D007674 | EFO_0003086 | N08 | — | — | — | — | 1 | 1 |
Fungal lung diseases | D008172 | EFO_0007278 | — | — | — | — | — | 1 | 1 |
Genetic predisposition to disease | D020022 | — | — | — | — | — | — | 1 | 1 |
Fusariosis | D060585 | EFO_1001795 | — | — | — | — | — | 1 | 1 |
Inflammation | D007249 | MP_0001845 | — | — | — | — | — | 1 | 1 |
Mucositis | D052016 | EFO_1001898 | — | — | — | — | — | 1 | 1 |
Lung transplantation | D016040 | — | — | — | — | — | — | 1 | 1 |
Covid-19 | D000086382 | — | U07.1 | — | — | — | — | 1 | 1 |
Drug common name | Posaconazole |
INN | posaconazole |
Description | Posaconazole, sold under the brand name Noxafil among others, is a triazole antifungal medication.
|
Classification | Small molecule |
Drug class | systemic antifungals (miconazole type) |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | CC[C@@H]([C@H](C)O)n1ncn(-c2ccc(N3CCN(c4ccc(OC[C@@H]5CO[C@@](Cn6cncn6)(c6ccc(F)cc6F)C5)cc4)CC3)cc2)c1=O |
PDB | — |
CAS-ID | 171228-49-2 |
RxCUI | — |
ChEMBL ID | CHEMBL1397 |
ChEBI ID | 64355 |
PubChem CID | 147912 |
DrugBank | DB01263 |
UNII ID | 6TK1G07BHZ (ChemIDplus, GSRS) |