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AboutPricing
Drug ReportsPosaconazole
Noxafil(posaconazole)
Noxafil, Posaconazole (posaconazole) is a small molecule pharmaceutical. Posaconazole was first approved as Noxafil on 2005-10-25. It is used to treat mycoses and oral candidiasis in the USA. It has been approved in Europe to treat aspergillosis, candidiasis, coccidioidomycosis, and mycoses.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
stomatognathic diseasesD009057
Trade Name
FDA
EMA
Noxafil, Posaconazole (discontinued: Noxafil, Posaconazole)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Posaconazole
Tradename
Company
Number
Date
Products
NOXAFILMerck & CoN-205596 RX2014-03-13
1 products, RLD, RS
NOXAFIL POWDERMIX KITMerck & CoN-214770 RX2021-05-31
1 products, RLD, RS
NOXAFILMerck & CoN-022003 RX2006-09-15
1 products, RLD, RS
Show 1 discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
noxafilNew Drug Application2024-10-25
posaconazoleANDA2025-01-15
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
mycoses—D009181B35-B49
oral candidiasisEFO_0007406D002180B37.0
Agency Specific
FDA
EMA
Expiration
Code
POSACONAZOLE, NOXAFIL, MERCK SHARP DOHME
2028-06-17ODE-355
2024-06-17I-881
2024-05-31NPP
POSACONAZOLE, NOXAFIL POWDERMIX KIT, MSD MERCK CO
2024-05-31NP
Patent Expiration
Patent
Expires
Flag
FDA Information
Posaconazole, Noxafil, Merck Sharp Dohme
94935822033-02-27DP
90237902031-07-04DPU-1698, U-3160, U-3171
93582972031-06-24DPU-3160, U-3171
84100772029-03-13DP
97508222029-03-13DP
101179512029-03-13DP
ATC Codes
J: Antiinfectives for systemic use
— J02: Antimycotics for systemic use
— J02A: Antimycotics for systemic use
— J02AC: Triazole and tetrazole derivatives
— J02AC04: Posaconazole
HCPCS
No data
Clinical
No data
Drug
General
Drug common namePosaconazole
INNposaconazole
Description
Posaconazole, sold under the brand name Noxafil among others, is a triazole antifungal medication.
Classification
Small molecule
Drug classsystemic antifungals (miconazole type)
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CC[C@@H]([C@H](C)O)n1ncn(-c2ccc(N3CCN(c4ccc(OC[C@@H]5CO[C@@](Cn6cncn6)(c6ccc(F)cc6F)C5)cc4)CC3)cc2)c1=O
Identifiers
PDB—
CAS-ID171228-49-2
RxCUI—
ChEMBL IDCHEMBL1397
ChEBI ID64355
PubChem CID147912
DrugBankDB01263
UNII ID6TK1G07BHZ (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
â‚£
Noxafil – Merck & Co
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Estimated US medical usage
Posaconazole
Total medical expenditures per year (USD, in millions)
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Trends
No data
Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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