Therapeutic Area | MeSH |
---|---|
infections | D007239 |
stomatognathic diseases | D009057 |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
NOXAFIL | Merck Sharp & Dohme | N-205053 RX | 2013-11-25 | 1 products, RLD, RS |
NOXAFIL | Merck Sharp & Dohme | N-205596 RX | 2014-03-13 | 1 products, RLD, RS |
NOXAFIL POWDERMIX KIT | Merck Sharp & Dohme | N-214770 RX | 2021-05-31 | 1 products, RLD, RS |
NOXAFIL | Merck Sharp & Dohme | N-022003 RX | 2006-09-15 | 1 products, RLD, RS |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
mycoses | — | D009181 | B35-B49 |
oral candidiasis | EFO_0007406 | D002180 | B37.0 |
Expiration | Code | ||
---|---|---|---|
POSACONAZOLE, NOXAFIL, MERCK SHARP DOHME | |||
2028-06-17 | ODE-355 | ||
2024-06-17 | I-881 | ||
2024-05-31 | NPP | ||
POSACONAZOLE, NOXAFIL POWDERMIX KIT, MSD MERCK CO | |||
2024-05-31 | NP |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Mycoses | D009181 | — | B35-B49 | 7 | 6 | 6 | 4 | 7 | 30 |
Myeloid leukemia acute | D015470 | — | C92.0 | 8 | 6 | 1 | 4 | 3 | 16 |
Myelodysplastic syndromes | D009190 | — | D46 | 2 | 4 | 1 | 2 | 1 | 8 |
Invasive pulmonary aspergillosis | D055744 | — | B44.0 | 1 | 1 | 2 | 1 | 1 | 6 |
Aspergillosis | D001228 | EFO_0007157 | B44 | — | 1 | 2 | 1 | 2 | 5 |
Invasive fungal infections | D000072742 | — | — | — | 1 | 1 | 1 | 2 | 5 |
Pharmacokinetics | D010599 | — | — | 2 | — | — | 1 | 1 | 4 |
Hematologic neoplasms | D019337 | — | — | — | 1 | 1 | 1 | 1 | 4 |
Infections | D007239 | EFO_0000544 | — | — | — | 1 | 1 | 1 | 3 |
Neutropenia | D009503 | — | D70 | 1 | — | 1 | 1 | — | 3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hiv infections | D015658 | EFO_0000764 | B20 | 1 | 1 | 1 | — | — | 3 |
Invasive hydatidiform mole | D002820 | — | D39.2 | — | — | 1 | — | 1 | 2 |
Cystic fibrosis | D003550 | EFO_0000390 | E84 | — | 1 | 1 | — | 1 | 2 |
Chronic granulomatous disease | D006105 | EFO_0000338 | D71 | — | 1 | 1 | — | — | 2 |
Oral candidiasis | D002180 | EFO_0007406 | B37.0 | — | 1 | 1 | — | — | 2 |
Candidemia | D058387 | EFO_1001282 | — | — | — | 1 | — | — | 1 |
Fungemia | D016469 | — | B49 | — | — | 1 | — | — | 1 |
Pneumocystis | D011010 | — | — | — | — | 1 | — | — | 1 |
Aspergillus | D001230 | — | — | — | — | 1 | — | — | 1 |
Leukopenia | D007970 | EFO_0004233 | D72.819 | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Leukemia | D007938 | — | C95 | 1 | 3 | — | — | — | 3 |
Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | C91.0 | 2 | 2 | — | — | — | 2 |
Onychomycosis | D014009 | — | B35.1 | — | 1 | — | — | 1 | 2 |
Chagas disease | D014355 | EFO_0008559 | B57 | — | 2 | — | — | — | 2 |
Myelomonocytic leukemia chronic | D015477 | — | C93.1 | 1 | 1 | — | — | — | 1 |
Graft vs host disease | D006086 | — | D89.81 | — | 1 | — | — | — | 1 |
Respiratory syncytial virus infections | D018357 | EFO_1001413 | — | — | 1 | — | — | — | 1 |
Mucormycosis | D009091 | EFO_0007380 | B46.5 | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Neoplasms | D009369 | — | C80 | 2 | — | — | — | — | 2 |
Healthy volunteers/patients | — | — | — | 1 | — | — | — | 1 | 2 |
Myeloid leukemia | D007951 | — | C92 | 1 | — | — | — | — | 1 |
Multiple myeloma | D009101 | — | C90.0 | 1 | — | — | — | — | 1 |
Lymphoma | D008223 | — | C85.9 | 1 | — | — | — | — | 1 |
Large b-cell lymphoma diffuse | D016403 | — | C83.3 | 1 | — | — | — | — | 1 |
Brain neoplasms | D001932 | EFO_0003833 | C71 | 1 | — | — | — | — | 1 |
Glioma | D005910 | EFO_0000520 | — | 1 | — | — | — | — | 1 |
Glioblastoma | D005909 | EFO_0000515 | — | 1 | — | — | — | — | 1 |
Hematopoietic stem cell transplantation | D018380 | — | — | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Critical illness | D016638 | — | — | — | — | — | — | 2 | 2 |
Hematologic diseases | D006402 | EFO_0005803 | D75.9 | — | — | — | — | 2 | 2 |
Kidney diseases | D007674 | EFO_0003086 | N08 | — | — | — | — | 1 | 1 |
Fungal lung diseases | D008172 | EFO_0007278 | — | — | — | — | — | 1 | 1 |
Candidiasis | D002177 | — | B37 | — | — | — | — | 1 | 1 |
Genetic predisposition to disease | D020022 | — | — | — | — | — | — | 1 | 1 |
Fusariosis | D060585 | EFO_1001795 | — | — | — | — | — | 1 | 1 |
Respiratory tract infections | D012141 | — | J06.9 | — | — | — | — | 1 | 1 |
Drug monitoring | D016903 | — | — | — | — | — | — | 1 | 1 |
Drug common name | Posaconazole |
INN | posaconazole |
Description | Posaconazole, sold under the brand name Noxafil among others, is a triazole antifungal medication.
|
Classification | Small molecule |
Drug class | systemic antifungals (miconazole type) |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | CC[C@@H]([C@H](C)O)n1ncn(-c2ccc(N3CCN(c4ccc(OC[C@@H]5CO[C@@](Cn6cncn6)(c6ccc(F)cc6F)C5)cc4)CC3)cc2)c1=O |
PDB | — |
CAS-ID | 171228-49-2 |
RxCUI | — |
ChEMBL ID | CHEMBL1397 |
ChEBI ID | 64355 |
PubChem CID | 147912 |
DrugBank | DB01263 |
UNII ID | 6TK1G07BHZ (ChemIDplus, GSRS) |