Pomalyst, Imnovid (previously pomalidomide celgene)(pomalidomide)
Imnovid, Pomalidomide, Pomalyst (pomalidomide) is a small molecule pharmaceutical. Pomalidomide was first approved as Pomalyst on 2013-02-08. It is used to treat kaposi sarcoma and multiple myeloma in the USA. It has been approved in Europe to treat multiple myeloma. It is known to target protein cereblon.
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Commercial
Therapeutic Areas
Trade Name
FDA
EMA
Pomalidomide, Pomalyst (discontinued: Pomalidomide)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Pomalidomide
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| POMALYST | Bristol Myers Squibb | N-204026 RX | 2013-02-08 | 4 products, RLD, RS |
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| pomalidomide | ANDA | 2026-01-30 |
| pomalyst | New Drug Application | 2025-02-26 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| multiple myeloma | — | D009101 | C90.0 |
Agency Specific
FDA
EMA
Expiration | Code | ||
|---|---|---|---|
POMALIDOMIDE, POMALYST, BRISTOL | |||
| 2027-11-14 | PED | ||
| 2027-05-14 | ODE-296, ODE-297 | ||
| 2024-05-20 | PED | ||
| 2023-11-20 | M-14 | ||
HCPCS
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Clinical
Clinical Trials
319 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Multiple myeloma | D009101 | — | C90.0 | 2 | — | — | — | — | 2 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Pomalidomide |
| INN | pomalidomide |
| Description | Pomalidomide is an aromatic amine that is thalidomide substituted at position 4 on the isoindole ring system by an amino group. Used for the treatment of multiple myeloma in patients who failed to respond to previous therapies. It has a role as an antineoplastic agent, an immunomodulator and an angiogenesis inhibitor. It is a dicarboximide, a member of isoindoles, a member of piperidones and an aromatic amine. It is functionally related to a thalidomide. |
| Classification | Small molecule |
| Drug class | thalidomide derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Nc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O |
Identifiers
| PDB | — |
| CAS-ID | 19171-19-8 |
| RxCUI | — |
| ChEMBL ID | CHEMBL43452 |
| ChEBI ID | 72690 |
| PubChem CID | 134780 |
| DrugBank | DB08910 |
| UNII ID | D2UX06XLB5 (ChemIDplus, GSRS) |
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Pomalyst – Bristol Myers Squibb
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Pomalyst – Celgene
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Estimated US medical usage
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PubMed Central
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Additional graphs summarizing 8,226 documents
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Safety
Black-box Warning
Black-box warning for: Pomalidomide, Pomalyst
Adverse Events
Top Adverse Reactions
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97,558 adverse events reported
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