Polytetrafluoroethylene
Skin Exposure Reduction Paste Against Chemical Warfare Agents (polytetrafluoroethylene) is a small molecule pharmaceutical. Polytetrafluoroethylene was first approved as Skin exposure reduction paste against chemical warfare agents on 2000-02-17.
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128 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hernia | D006547 | — | K40-K46 | — | — | 1 | 2 | 4 | 7 |
| Tooth loss | D016388 | — | — | — | 1 | 1 | 1 | 3 | 5 |
| Ischemia | D007511 | EFO_0000556 | — | — | — | — | 1 | 1 | 2 |
| Chronic limb-threatening ischemia | D000089802 | — | — | — | — | — | 1 | 1 | 2 |
| Peripheral catheterization | D002406 | — | — | — | — | — | 1 | 1 | 2 |
| Inguinal hernia | D006552 | HP_0000023 | K40 | — | — | — | 1 | 1 | 2 |
| Acute coronary syndrome | D054058 | EFO_0005672 | — | — | — | — | 1 | — | 1 |
| Syndrome | D013577 | — | — | — | — | — | 1 | — | 1 |
| Dehydration | D003681 | — | E86.0 | — | — | — | 1 | — | 1 |
| Ventral hernia | D006555 | EFO_1001866 | K43 | — | — | — | 1 | — | 1 |
Show 6 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Alveolar bone loss | D016301 | — | — | — | 2 | 1 | — | 3 | 5 |
| Edentulous mouth | D009066 | — | — | — | — | 1 | — | 1 | 2 |
| Hiatal hernia | D006551 | EFO_0007216 | K44 | — | — | 1 | — | 1 | 2 |
| Peri-implantitis | D057873 | EFO_1001390 | — | — | — | 1 | — | 1 | 2 |
| Peripheral nerve injuries | D059348 | — | — | — | 1 | 1 | — | — | 1 |
| Pyloric stenosis | D011707 | — | K31.1 | — | — | 1 | — | — | 1 |
| Gastric outlet obstruction | D017219 | EFO_1000947 | — | — | — | 1 | — | — | 1 |
| Periodontal diseases | D010510 | — | K05.6 | — | — | 1 | — | — | 1 |
| Hyperemia | D006940 | EFO_0003822 | H34.82 | — | 1 | 1 | — | — | 1 |
| Metabolic bone diseases | D001851 | — | — | — | — | 1 | — | — | 1 |
Show 3 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | 1 | 1 | — | — | 4 | 5 |
| Fibrosis | D005355 | — | — | — | 1 | — | — | 3 | 4 |
| Chronic kidney failure | D007676 | EFO_0003884 | N18.6 | 1 | 2 | — | — | 2 | 4 |
| Renal insufficiency | D051437 | — | N19 | 1 | 1 | — | — | 3 | 4 |
| Liver cirrhosis | D008103 | EFO_0001422 | K74.0 | — | 1 | — | — | 2 | 3 |
| Tissue adhesions | D000267 | — | — | — | 1 | — | — | 1 | 2 |
| Psoriasis | D011565 | EFO_0000676 | L40 | — | 2 | — | — | — | 2 |
| Proctitis | D011349 | EFO_0005628 | K62.89 | — | 1 | — | — | — | 1 |
| Telangiectasis | D013684 | — | — | — | 1 | — | — | — | 1 |
| Radiation injuries | D011832 | — | T66 | — | 1 | — | — | — | 1 |
Show 8 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Dental implants | D015921 | — | — | 1 | — | — | — | 2 | 3 |
| Soft tissue injuries | D017695 | — | — | 1 | — | — | — | 1 | 2 |
| Urinary bladder neoplasms | D001749 | — | C67 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Inflammation | D007249 | MP_0001845 | — | — | — | — | — | 4 | 4 |
| Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | — | — | — | — | 3 | 3 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | — | — | — | 3 | 3 |
| Heart failure | D006333 | EFO_0003144 | I50 | — | — | — | — | 3 | 3 |
| Hemorrhage | D006470 | MP_0001914 | R58 | — | — | — | — | 3 | 3 |
| Tooth extraction | D014081 | — | — | — | — | — | — | 3 | 3 |
| Tissue preservation | D014021 | — | — | — | — | — | — | 3 | 3 |
| Prolapse | D011391 | — | — | — | — | — | — | 3 | 3 |
| Atrophy | D001284 | — | — | — | — | — | — | 3 | 3 |
| Peripheral arterial disease | D058729 | EFO_0004265 | — | — | — | — | — | 3 | 3 |
Show 103 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Polytetrafluoroethylene |
| INN | politef |
| Description | Polytetrafluoroethylene (PTFE) is a synthetic fluoropolymer of tetrafluoroethylene. It belongs to the per- and polyfluoroalkyl substances (PFAS)) and has numerous applications. The commonly known brand name of PTFE-based composition is Teflon by Chemours, a spin-off from DuPont, which originally discovered the compound in 1938.
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 9002-84-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1201480 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | E1NC1JVS3O (ChemIDplus, GSRS) |
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