Polytetrafluoroethylene
Skin Exposure Reduction Paste Against Chemical Warfare Agents (polytetrafluoroethylene) is a small molecule pharmaceutical. Polytetrafluoroethylene was first approved as Skin exposure reduction paste against chemical warfare agents on 2000-02-17.
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Clinical Trials
211 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Fibrosis | D005355 | — | — | — | 1 | — | 1 | 7 | 9 |
| Vascular diseases | D014652 | EFO_0004264 | I77 | — | — | — | 3 | 5 | 8 |
| Peripheral arterial disease | D058729 | EFO_0004265 | — | — | — | — | 1 | 7 | 8 |
| Hernia | D006547 | — | K40-K46 | — | — | 1 | 2 | 5 | 8 |
| Ischemia | D007511 | EFO_0000556 | — | — | — | 1 | 2 | 4 | 7 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | 1 | 1 | — | 1 | 5 | 7 |
| Arterial occlusive diseases | D001157 | EFO_0009085 | — | — | — | — | 1 | 5 | 6 |
| Peripheral vascular diseases | D016491 | EFO_0003875 | I73.9 | — | — | — | 1 | 5 | 6 |
| Liver cirrhosis | D008103 | EFO_0001422 | K74.0 | — | 1 | — | 1 | 4 | 6 |
| Tooth loss | D016388 | — | — | — | 1 | 1 | 1 | 4 | 6 |
Show 21 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Alveolar bone loss | D016301 | — | — | — | 2 | 2 | — | 8 | 11 |
| Peri-implantitis | D057873 | EFO_1001390 | — | — | — | 1 | — | 3 | 4 |
| Atherosclerosis | D050197 | EFO_0003914 | I25.1 | — | — | 1 | — | 2 | 3 |
| Edentulous mouth | D009066 | — | — | — | — | 1 | — | 1 | 2 |
| Hiatal hernia | D006551 | EFO_0007216 | K44 | — | — | 1 | — | 1 | 2 |
| Bone resorption | D001862 | — | — | — | — | 1 | — | 1 | 2 |
| Periodontitis | D010518 | EFO_0000649 | K05.3 | — | — | 1 | — | 1 | 2 |
| Peripheral nerve injuries | D059348 | — | — | — | 1 | 1 | — | — | 1 |
| Pyloric stenosis | D011707 | — | K31.1 | — | — | 1 | — | — | 1 |
| Gastric outlet obstruction | D017219 | EFO_1000947 | — | — | — | 1 | — | — | 1 |
Show 8 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic kidney failure | D007676 | EFO_0003884 | N18.6 | 1 | 3 | — | — | 4 | 7 |
| Atrophy | D001284 | — | — | — | 1 | — | — | 6 | 7 |
| Renal insufficiency | D051437 | — | N19 | 1 | 1 | — | — | 3 | 4 |
| Tissue adhesions | D000267 | — | — | — | 1 | — | — | 1 | 2 |
| Psoriasis | D011565 | EFO_0000676 | L40 | — | 2 | — | — | — | 2 |
| Kidney diseases | D007674 | EFO_0003086 | N08 | — | 2 | — | — | — | 2 |
| Proctitis | D011349 | EFO_0005628 | K62.89 | — | 1 | — | — | — | 1 |
| Telangiectasis | D013684 | — | — | — | 1 | — | — | — | 1 |
| Radiation injuries | D011832 | — | T66 | — | 1 | — | — | — | 1 |
| Malignant pleural effusion | D016066 | — | J91.0 | 1 | 1 | — | — | — | 1 |
Show 5 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Dental implants | D015921 | — | — | 1 | — | — | — | 7 | 8 |
| Soft tissue injuries | D017695 | — | — | 1 | — | — | — | 1 | 2 |
| Urinary incontinence | D014549 | — | R32 | 1 | — | — | — | 1 | 2 |
| Urinary bladder neoplasms | D001749 | — | C67 | 1 | — | — | — | — | 1 |
| Urinary retention | D016055 | — | R33 | 1 | — | — | — | — | 1 |
| Spinal cord injuries | D013119 | EFO_1001919 | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Portal hypertension | D006975 | EFO_0000666 | K76.6 | — | — | — | — | 5 | 5 |
| Tooth extraction | D014081 | — | — | — | — | — | — | 5 | 5 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | — | — | — | 4 | 4 |
| Inflammation | D007249 | MP_0001845 | — | — | — | — | — | 4 | 4 |
| Ascites | D001201 | — | R18 | — | — | — | — | 4 | 4 |
| Pathologic constriction | D003251 | — | — | — | — | — | — | 4 | 4 |
| Aneurysm | D000783 | — | I72.9 | — | — | — | — | 4 | 4 |
| Aortic dissection | D000784 | — | I71.0 | — | — | — | — | 4 | 4 |
| Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | — | — | — | — | 3 | 3 |
| Heart failure | D006333 | EFO_0003144 | I50 | — | — | — | — | 3 | 3 |
Show 129 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Polytetrafluoroethylene |
| INN | politef |
| Description | Polytetrafluoroethylene (PTFE) is a synthetic fluoropolymer of tetrafluoroethylene. It belongs to the per- and polyfluoroalkyl substances (PFAS)) and has numerous applications. The commonly known brand name of PTFE-based composition is Teflon by Chemours, a spin-off from DuPont, which originally discovered the compound in 1938.
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 9002-84-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1201480 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | E1NC1JVS3O (ChemIDplus, GSRS) |
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