Polihexanide
Polihexanide is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Trade Name
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| alcohol free antibacterial hand sanitizer | unapproved drug other | 2022-03-08 |
| drop dream eye 2 | unapproved drug other | 2024-05-28 |
| hba anti bacterial liquid | unapproved drug other | 2020-07-22 |
| hba sanitary wipes | unapproved drug other | 2020-07-22 |
| phmb disinfectant | unapproved drug other | 2020-05-22 |
| wash free hand sanitizer(alcohol free) | unapproved drug other | 2020-03-30 |
Indications
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Agency Specific
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Clinical
Clinical Trials
49 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
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Indications Phases 1
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Diabetes complications | D048909 | — | — | — | — | — | — | 1 | 1 |
| Leg ulcer | D007871 | — | — | — | — | — | — | 1 | 1 |
| Wounds and injuries | D014947 | — | T14.8 | — | — | — | — | 1 | 1 |
| Varicose ulcer | D014647 | — | — | — | — | — | — | 1 | 1 |
| Ulcer | D014456 | MPATH_579 | — | — | — | — | — | 1 | 1 |
| Wound healing | D014945 | GO_0042060 | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Polihexanide |
| INN | polihexanide |
| Description | Polyhexanide (polyhexamethylene biguanide, PHMB) is a polymer used as a disinfectant and antiseptic. In dermatological use, it is spelled polihexanide (INN) and sold under the names Lavasept, Serasept, Prontosan, and Omnicide. PHMB has been shown to be effective against Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Candida albicans, Aspergillus brasiliensis, enterococci, and Klebsiella pneumoniae.
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| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCCCCCNC(=N)NC(=N)N |
Identifiers
| PDB | — |
| CAS-ID | 28757-47-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2106939 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB12277 |
| UNII ID | 322U039GMF (ChemIDplus, GSRS) |
Target
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Trends
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Safety
Black-box Warning
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Adverse Events
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71 adverse events reported
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