Podofilox
Condylox, Podofilox (podofilox) is a small molecule pharmaceutical. Podofilox was first approved as Condylox on 1990-12-13. It is used to treat warts in the USA. The pharmaceutical is active against insulin-like growth factor 1 receptor.
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| infections | D007239 |
| skin and connective tissue diseases | D017437 |
Trade Name
FDA
EMA
Condylox, Podofilox (discontinued: Podofilox)
Drug Products
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Agency Specific
FDA
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Patent Expiration
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ATC Codes
D: Dermatologicals
— D06: Antibiotics and chemotherapeutics for dermatological use
— D06B: Chemotherapeutics for topical use
— D06BB: Antivirals, topical
— D06BB04: Podophyllotoxin
L: Antineoplastic and immunomodulating agents
— L01: Antineoplastic agents
— L01C: Plant alkaloids and other natural products, antineoplastic drugs
— L01CB: Podophyllotoxin derivatives, antineoplastic drugs
HCPCS
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Clinical
Clinical Trials
1422 clinical trials
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Indications Phases 4
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Indications Phases 3
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Podofilox |
| INN | — |
| Description | Podophyllotoxin is an organic heterotetracyclic compound that has a furonaphthodioxole skeleton bearing a 3,4,5-trimethoxyphenyl substituent. It is found in the roots and rhizomes of Podophyllum species and is used for the topical treatment of genital warts. It has a role as an antineoplastic agent, a keratolytic drug, a tubulin modulator, a microtubule-destabilising agent, an antimitotic and a plant metabolite. It is a furonaphthodioxole, a lignan and an organic heterotetracyclic compound. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | COc1cc([C@@H]2c3cc4c(cc3[C@H](O)[C@H]3COC(=O)[C@H]23)OCO4)cc(OC)c1OC |
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Financial
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Estimated US medical usage
Podofilox
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105 adverse events reported
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