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Drug ReportsPirarubicin
Pirarubicin
Pirarubicin is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
L: Antineoplastic and immunomodulating agents
L01: Antineoplastic agents
L01D: Cytotoxic antibiotics and related substances
L01DB: Anthracyclines and related substances
L01DB08: Pirarubicin
HCPCS
No data
Clinical
No data
Drug
General
Drug common namePirarubicin
INNpirarubicin
Description
Pirarubicin (INN) is an anthracycline drug. An analogue of the anthracycline antineoplastic antibiotic doxorubicin. Pirarubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent is less cardiotoxic than doxorubicin and exhibits activity against some doxorubicin-resistant cell lines.
Classification
Small molecule
Drug classantineoplastic antibiotics (daunorubicin type)
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@H](O[C@@H]2CCCCO2)[C@H](C)O1
Identifiers
PDB
CAS-ID72496-41-4
RxCUI
ChEMBL IDCHEMBL2354444
ChEBI ID
PubChem CID3033521
DrugBank
UNII IDD58G680W0G (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
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Trends
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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