Piperaquine tetraphosphate
Eurartesim (piperaquine tetraphosphate) is a small molecule pharmaceutical. Piperaquine tetraphosphate was first approved as Eurartesim on 2011-10-27. It has been approved in Europe to treat malaria.
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| infections | D007239 |
Trade Name
FDA
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Agency Specific
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ATC Codes
P: Antiparasitic products, insecticides and repellents
— P01: Antiprotozoals
— P01B: Antimalarials
— P01BF: Artemisinin and derivatives, combinations
— P01BF05: Artenimol and piperaquine
— P01BF07: Artemisinin and piperaquine
— P01BX: Other antimalarials in atc
— P01BX02: Arterolane and piperaquine
HCPCS
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Clinical
Clinical Trials
170 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Malaria | D008288 | EFO_0001068 | B54 | 1 | 1 | 1 | — | — | 3 |
| Vivax malaria | D016780 | EFO_0007445 | B51 | 1 | — | 1 | — | — | 2 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Falciparum malaria | D016778 | EFO_0007444 | B50 | — | 1 | — | — | — | 1 |
Indications Phases 1
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Piperaquine tetraphosphate |
| INN | — |
| Description | Piperaquine is an aminoquinoline that is 1,3-di(piperazin-1-yl)propane in which the nitrogen at position 4 of each of the piperazine moieties is replaced by a 7-chloroquinolin-4-yl group. It has a role as an antimalarial. It is a N-arylpiperazine, an organochlorine compound and an aminoquinoline. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Clc1ccc2c(N3CCN(CCCN4CCN(c5ccnc6cc(Cl)ccc56)CC4)CC3)ccnc2c1.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O |
Identifiers
| PDB | — |
| CAS-ID | 4085-31-8 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1652442 |
| ChEBI ID | — |
| PubChem CID | 122262 |
| DrugBank | DB13941 |
| UNII ID | — |
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Safety
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39 adverse events reported
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