Pexelizumab
Pexelizumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target complement C5.
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Events Timeline
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Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
3 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Myocardial infarction | D009203 | EFO_0000612 | I21 | — | — | 1 | — | — | 1 |
| Infarction | D007238 | EFO_0009463 | — | — | — | 1 | — | — | 1 |
| Inferior wall myocardial infarction | D056989 | EFO_1000983 | — | — | — | 1 | — | — | 1 |
| Coronary artery disease | D003324 | — | I25.1 | — | — | 1 | — | — | 1 |
| Cardiopulmonary bypass | D002315 | — | — | — | — | 1 | — | — | 1 |
| Coronary artery bypass | D001026 | EFO_0003776 | — | — | — | 1 | — | — | 1 |
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Pexelizumab |
| INN | pexelizumab |
| Description | Pexelizumab (humanized scFv) |
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2107979 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | CHZ6OLQ3UU (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
C5
C5
Organism
Homo sapiens
Gene name
C5
Gene synonyms
CPAMD4
NCBI Gene ID
Protein name
complement C5
Protein synonyms
anaphylatoxin C5a analog, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, C5a anaphylatoxin, complement component 5, prepro-C5
Uniprot ID
Mouse ortholog
Hc (15139)
complement C5 (P06684)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 440 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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