Pexacerfont
Pexacerfont is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target CRHR1-IT1-CRHR1 protein.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
No data
Clinical
Clinical Trials
14 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
No data
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Anxiety disorders | D001008 | EFO_0006788 | F41.1 | — | 2 | 1 | — | 1 | 3 |
| Hyperplasia | D006965 | EFO_0000536 | — | — | — | 2 | — | — | 2 |
| Congenital adrenal hyperplasia | D000312 | — | E25.0 | — | — | 2 | — | — | 2 |
| Adrenogenital syndrome | D047808 | — | E25.9 | — | — | 2 | — | — | 2 |
| Adrenocortical hyperfunction | D000308 | EFO_1000797 | — | — | — | 2 | — | — | 2 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Irritable bowel syndrome | D043183 | EFO_0000555 | K58 | 1 | 2 | — | — | — | 3 |
| Alcoholism | D000437 | EFO_0003829 | F10.1 | — | 2 | — | — | — | 2 |
| Post-traumatic stress disorders | D013313 | EFO_0001358 | F43.1 | — | 2 | — | — | — | 2 |
| Traumatic stress disorders | D040921 | — | — | — | 2 | — | — | — | 2 |
| Syndrome | D013577 | — | — | 1 | 1 | — | — | — | 2 |
| Alcohol-related disorders | D019973 | — | F10 | — | 1 | — | — | — | 1 |
| Depression | D003863 | — | F33.9 | 1 | 1 | — | — | — | 1 |
| Major depressive disorder | D003865 | EFO_0003761 | F22 | 1 | 1 | — | — | — | 1 |
| Depressive disorder | D003866 | EFO_1002014 | F32.A | 1 | 1 | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Tobacco use disorder | D014029 | — | F17 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Pexacerfont |
| INN | pexacerfont |
| Description | Pexacerfont is a pyrazolopyridine. |
| Classification | Small molecule |
| Drug class | CRF-1 (corticotropin releasing factor) receptor antagonists |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC[C@@H](C)Nc1nc(C)nc2c(-c3ccc(OC)nc3C)c(C)nn12 |
Identifiers
| PDB | — |
| CAS-ID | 459856-18-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL482950 |
| ChEBI ID | — |
| PubChem CID | 9884366 |
| DrugBank | DB12572 |
| UNII ID | LF1VBG4ZUK (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
LINC02210-CRHR1
LINC02210-CRHR1
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 661 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
© 2020-2024 Collaborative Drug Discovery Inc. (CDD) | Terms of Use