Tradename | Company | Number | Date | Products |
---|---|---|---|---|
PRESTALIA | Adhera Therapeutics | N-205003 RX | 2015-01-21 | 3 products, RLD, RS |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
ACEON | Symplmed Pharmaceuticals | N-020184 DISCN | 1993-12-30 | 3 products, RLD |
Brand Name | Status | Last Update |
---|---|---|
prestalia | New Drug Application | 2019-10-25 |
Patent | Expires | Flag | FDA Information |
---|---|---|---|
Amlodipine Besylate / Perindopril Arginine, Prestalia, Adhera | |||
7846961 | 2029-10-05 | DS, DP | U-3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hypertension | D006973 | EFO_0000537 | I10 | — | 3 | 3 | 15 | 6 | 27 |
Essential hypertension | D000075222 | — | I10 | — | — | 4 | 1 | 3 | 8 |
Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | — | 1 | 4 | — | 5 |
Chronic renal insufficiency | D051436 | — | N18 | — | — | — | 3 | 1 | 4 |
Covid-19 | D000086382 | — | U07.1 | — | — | 1 | 1 | 1 | 3 |
Heart failure | D006333 | HP_0001635 | I50 | 1 | 1 | — | 1 | 1 | 3 |
Blood pressure | D001794 | EFO_0004325 | — | — | — | — | 2 | 1 | 3 |
Atrial fibrillation | D001281 | EFO_0000275 | I48.0 | — | — | 1 | 1 | 1 | 3 |
Myocardial infarction | D009203 | EFO_0000612 | I21 | — | — | — | 1 | 1 | 2 |
Dyslipidemias | D050171 | HP_0003119 | — | — | — | 1 | 1 | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Cardiovascular diseases | D002318 | HP_0001626 | — | — | — | 1 | — | 2 | 3 |
Pneumonia | D011014 | EFO_0003106 | — | — | — | 1 | — | — | 1 |
Dilated cardiomyopathy | D002311 | HP_0001644 | I42.0 | — | — | 1 | — | — | 1 |
Non-small-cell lung carcinoma | D002289 | — | — | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Aging | D000375 | GO_0007568 | R41.81 | — | 1 | — | — | 1 | 2 |
Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | 2 | — | — | — | 2 |
Ischemic stroke | D000083242 | — | — | — | 1 | — | — | 1 | 2 |
Obesity | D009765 | EFO_0001073 | E66.9 | — | 1 | — | — | 1 | 2 |
Sedentary behavior | D057185 | — | — | — | 1 | — | — | — | 1 |
Alzheimer disease | D000544 | EFO_0000249 | F03 | — | 1 | — | — | — | 1 |
Transient ischemic attack | D002546 | EFO_0003764 | G45.9 | — | 1 | — | — | — | 1 |
Abdominal aortic aneurysm | D017544 | EFO_0004214 | — | — | 1 | — | — | — | 1 |
Colorectal neoplasms | D015179 | — | — | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 4 | — | — | — | 1 | 5 |
Therapeutic equivalency | D013810 | — | — | 2 | — | — | — | — | 2 |
Substance-related disorders | D019966 | EFO_0003890 | F13 | 1 | — | — | — | — | 1 |
Post-traumatic stress disorders | D013313 | EFO_0001358 | F43.1 | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Cognitive dysfunction | D060825 | HP_0001268 | G31.84 | — | — | — | — | 2 | 2 |
Metabolic bone diseases | D001851 | HP_0000938 | — | — | — | — | — | 1 | 1 |
Coronary artery disease | D003324 | — | I25.1 | — | — | — | — | 1 | 1 |
Patient participation | D010358 | — | — | — | — | — | — | 1 | 1 |
Coronary disease | D003327 | — | — | — | — | — | — | 1 | 1 |
Subdural hematoma chronic | D020200 | — | — | — | — | — | — | 1 | 1 |
Diabetes mellitus | D003920 | HP_0000819 | E08-E13 | — | — | — | — | 1 | 1 |
Vascular diseases | D014652 | EFO_0004264 | I77 | — | — | — | — | 1 | 1 |
Cardio-renal syndrome | D059347 | — | — | — | — | — | — | 1 | 1 |
Drug common name | Perindopril |
INN | perindopril |
Description | Perindopril is an alpha-amino acid ester that is the ethyl ester of N-{(2S)-1-[(2S,3aS,7aS)-2-carboxyoctahydro-1H-indol-1-yl]-1-oxopropan-2-yl}-L-norvaline It has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor and an antihypertensive agent. It is an alpha-amino acid ester, a dicarboxylic acid monoester, an organic heterobicyclic compound and an ethyl ester. It is a conjugate acid of a perindopril(1-). |
Classification | Small molecule |
Drug class | antihypertensives (ACE inhibitors) |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | CCC[C@H](N[C@@H](C)C(=O)N1[C@H](C(=O)O)C[C@@H]2CCCC[C@@H]21)C(=O)OCC |
PDB | — |
CAS-ID | 82834-16-0 |
RxCUI | — |
ChEMBL ID | CHEMBL1581 |
ChEBI ID | 8024 |
PubChem CID | 107807 |
DrugBank | DB00790 |
UNII ID | Y5GMK36KGY (ChemIDplus, GSRS) |