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Drug ReportsPerflubutane
Perflubutane
Perflubutane is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Events Timeline
5D
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Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
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EMA
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Indications
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
V: Various drug classes in atc
— V08: Contrast media
— V08D: Ultrasound contrast media
— V08DA: Ultrasound contrast media
— V08DA06: Perflubutane, phospholipid microspheres
HCPCS
No data
Clinical
Clinical Trials
65 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Liver neoplasmsD008113EFO_1001513C22.0——1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Heart failureD006333EFO_0003144I50—1———1
Blood pressureD001794EFO_0004325——1———1
Cardiac catheterizationD006328———1———1
EchocardiographyD004452———1———1
Kidney transplantationD016030———1———1
Breast neoplasmsD001943EFO_0003869C5011———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
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Total
Healthy volunteers/patients———1————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
CarcinomaD002277—C80.0————11
Hepatocellular carcinomaD006528—C22.0————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common namePerflubutane
INNperflubutane
Description
Perflubutane is a fluorocarbon that is butane in which all of the hydrogens have been replaced by fluorines. Microbubbles of preflubutane are used in the ultrasound contrast agent BR14. It has a role as an ultrasound contrast agent. It is a gas molecular entity, a fluorocarbon and a fluoroalkane.
Classification
Small molecule
Drug classblood substitutes and/or diagnostics (perfluorochemicals)
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Structure (InChI/SMILES or Protein Sequence)
FC(F)(F)C(F)(F)C(F)(F)C(F)(F)F
Identifiers
PDB—
CAS-ID355-25-9
RxCUI—
ChEMBL IDCHEMBL2104979
ChEBI ID—
PubChem CID9638
DrugBank—
UNII IDSE4TWR0K2C (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1,813 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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2 adverse events reported
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